Science
Mechanism of Action
This extract operates via several biological pathways, contributing to improved skin condition. It functions as an antioxidant, neutralizing damaging free radicals and mitigating oxidative stress. Active compounds like hinokitiol and beta-dolobrin confer antibacterial effects, helping to purify the skin. Furthermore, studies indicate its ability to modulate inflammatory responses by inhibiting IgE and histamine production, offering relief for sensitive or reactive skin. The extract also demonstrates potential to inhibit tyrosinase activity, thereby reducing melanin synthesis and the appearance of hyperpigmentation. Its capacity to inhibit lipoxygenase may help regulate sebum production, benefiting oily skin, while MMP-1 inhibition suggests a role in preserving collagen and elastin, thus addressing concerns like fine lines and sagging.
Research
Clinical Evidence
Medium confidence6%
Key findings
- 01 Significant reduction in AD-like skin lesions and inflammatory markers.
- 02 Demonstrated high antioxidant activity.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has not yet published an assessment for Thujopsis Dolabrata Branch Extract. The EWG Skin Deep database rates a related 'Thujopsis Dolabrata Extract' with a LOW hazard score for concerns including cancer, allergies & immunotoxicity, and developmental and reproductive toxicity, though it indicates 'LIMITED-FAIR' data availability. No GHS hazard classifications were identified, and oral, dermal, and inhalation toxicity data were 'Not determined'.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Thujopsis Dolabrata Branch Extract is a valuable ingredient, demonstrating significant anti-inflammatory and antioxidant benefits, alongside potential for addressing hyperpigmentation, sebum control, and signs of aging.
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