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Moumoujus

THUJA PLICATA WOOD OIL.

Valuable CAS 68917-35-1 / FRAGRANCE

This precision botanical extract, derived exclusively from the wood of Thuja plicata, offers multifaceted benefits for skin health. It demonstrates significant anti-inflammatory and immunomodulatory properties, coupled with tissue-remodeling and purifying effects for balanced skin.

Summary

Anti-inflammatory Immunomodulatory Tissue Remodeling Antiproliferative Antioxidant Purifying Cleansing Toning Regenerative Antimicrobial Scar Reduction

Science

Mechanism of Action

Thuja Plicata Wood Oil, notably rich in methyl thujate, acts by modulating key inflammatory and immune responses within human dermal fibroblasts. Studies indicate its ability to significantly suppress pro-inflammatory biomarkers such as VCAM-1, ICAM-1, IP-10, I-TAC, MIG, and M-CSF. Furthermore, it exhibits antiproliferative activity and inhibits collagen-I, collagen-III, PAI-1, TIMP-1, and TIMP-2, suggesting a role in tissue remodeling and potentially scar reduction. Its antioxidant and flavonoid content provides protection against oxidative stress, while its inherent purifying, cleansing, and toning qualities contribute to balancing problematic and oily complexions. The oil is also recognized for regenerative and antimicrobial attributes, supporting wound healing and addressing various skin imperfections.

Research

Clinical Evidence

Medium confidence
Effective range 0.011–5%
Optimal

0.011%

Key findings

  1. 01 In a pre-inflamed human dermal fibroblast culture, Arborvitae (Thuja plicata) essential oil at 0.011% significantly inhibited the expression of multiple inflammatory and tissue remodeling-related proteins (e.g., VCAM-1, ICAM-1, IP-10, I-TAC, MIG, M-CSF) and genes. It also demonstrated antiproliferative activity and inhibited collagen-I, collagen-III, PAI-1, TIMP-1, and TIMP-2.
  2. 02 Topical concentrations between 0.5% and 2% are suggested for skincare products like facial cleansers, toners, or spot treatments to balance and refresh oily and acne-prone complexions.
  3. 03 For scalp care, concentrations of 0.5% to 1% are recommended for purifying and balancing effects in scalp treatments or shampoos.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

To preserve freshness and maximize shelf life, store this essential oil in dark glass containers, protecting it from light and air exposure.

Conflicts

  • Direct, undiluted application to skin (may cause irritation).
  • Use during pregnancy and lactation (general caution for Thuja plicata essential oils).
  • Use with babies, children, and the elderly (general caution for Thuja plicata essential oils).
  • Individuals with known allergy or sensitivity to Thujone (though 'wood only' oil is reported to be thujone-free, general caution for Thuja species).

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
5%
Pregnancy
Caution
Sensitization risk Low

Thuja Plicata Wood Oil, derived exclusively from the wood, is distinct as it reportedly contains no thujone, a compound often found in essential oils from other parts of the Thuja plicata plant or other Thuja species, which can be toxic and irritating. Despite its thujone-free nature, dilution is essential for topical application to minimize irritation risk, and a patch test is recommended. Broader cautions applicable to 'Thuja Plicata essential oil' advise against use during pregnancy and lactation due to potential emmenagogue properties, and with infants, children, or the elderly. These broader considerations warrant caution, despite the 'wood oil' specificity.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Thuja Plicata Wood Oil offers significant anti-inflammatory, immunomodulatory, and tissue-remodeling benefits for the skin, particularly for balancing problematic complexions, provided it is properly diluted and applied with consideration for general essential oil precautions.

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