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Moumoujus

THUJA OCCIDENTALIS LEAF EXTRACT.

Valuable CAS 90131-58-1 / ANTIOXIDANT, BLEACHING, HAIR CONDITIONING, PERFUMING, SKIN CONDITIONING

Thuja Occidentalis Leaf Extract is a botanical ingredient renowned for its multifaceted benefits, including potent antioxidant and anti-inflammatory capabilities. It functions as a skin conditioning agent, supporting skin health, clarity, and comfort while also exhibiting antimicrobial properties.

Summary

Antioxidant Skin Conditioning Anti-inflammatory Antimicrobial Astringent Soothing

Science

Mechanism of Action

This extract operates as a robust antioxidant, actively neutralizing free radicals to combat oxidative stress, cellular damage, and premature aging processes. Its anti-inflammatory action is achieved by modulating key mediators such as histamine and PGE2, diminishing vascular permeability, and reducing pro-inflammatory cytokines like TNF-α and IL-6. Furthermore, it possesses antibacterial, antifungal, and antiviral qualities, contributes to skin conditioning, and provides astringent and soothing effects.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vitro studies confirmed antioxidant activity, showing inhibition of lipid peroxidation induced by FeSO4, with ethanolic fractions effective at concentrations from 100 to 300 μg.
  2. 02 Dose-dependent antimicrobial effects were observed in vitro against various microorganisms, demonstrating significant zones of inhibition.
  3. 03 In vitro antiviral activity was reported for the leaf extract, resulting in 17.7% and 16.2% suppression rates against herpes simplex and influenza viruses, respectively.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Formulated ointments containing Thuja Occidentalis Leaf Extract have demonstrated robust physical stability, maintaining consistent visual appearance, viscosity, homogeneity, and aroma without signs of phase separation over a research period. The extract exhibits versatile solubility, with certain forms being hydrosoluble and essential oil components being oil-soluble.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While the Cosmetic Ingredient Review (CIR) has not formally reviewed this ingredient, the EU Scientific Committee on Consumer Safety (SCCS) has evaluated its use in cosmetic products. Its topical application is considered safe, provided specific restrictions regarding purity criteria and maximum concentrations are adhered to. This is primarily due to the presence of thujone in the plant, which at high concentrations, particularly if ingested, can lead to adverse metabolic disturbances and irritant effects. The Environmental Working Group (EWG) rates it as a low concern for cancer, allergies, immunotoxicity, and developmental/reproductive toxicity, while also noting high use restrictions based on EU Cosmetics Directive guidelines.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Thuja Occidentalis Leaf Extract is a valuable botanical ingredient, offering significant antioxidant, anti-inflammatory, and antimicrobial benefits for skin conditioning, although its formulation must carefully adhere to established cosmetic restrictions.

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