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THEOBROMA GRANDIFLORUM FRUIT EXTRACT.

Valuable CAS 394236-97-6 / SKIN CONDITIONING

Theobroma Grandiflorum Fruit Extract, derived from the Amazonian Cupuaçu fruit, is a multifaceted ingredient rich in beneficial fatty acids, phytosterols, and a broad spectrum of antioxidants. It is engineered to intensely hydrate, enhance skin elasticity, and promote cellular regeneration. This extract also offers notable photoprotective and anti-inflammatory properties.

Summary

Antioxidant Skin-Conditioning Agent Emollient Soothing

Science

Mechanism of Action

This extract operates through several precise pathways: it deeply moisturizes by leveraging its exceptional water-retention capacity, thereby reinforcing the skin's natural barrier function. It actively stimulates cellular renewal and migration, evidenced by the upregulation of key reparative genes such as MKI67 (a cellular proliferation marker), ELN (for elastin synthesis), and HAS2 (for hyaluronic acid production). Furthermore, its rich profile of antioxidants, including polyphenols, flavonoids, and vitamins C and E, provides robust protection against oxidative stress and acts as a natural filter against UVB radiation, complemented by inherent anti-inflammatory benefits.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

The extract, particularly when precisely incorporated into nanocapsules, demonstrates remarkable physical stability, verified for over 120 days. Cupuaçu butter, a related derivative, also functions as a stabilizer in cosmetic emulsions, actively preventing stratification. Nanoparticle formulations (e.g., VM-Theospheres) maintain stability for at least 28 days at room temperature, with an average particle size of 274 ± 5 nm.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While a specific CIR status for Theobroma Grandiflorum Fruit Extract is currently pending review, its related derivative, Cupuaçu seed butter, is widely recognized as a safe ingredient. It exhibits no irritation, sensitivity, or comedogenic properties and is well-tolerated by all skin types, including sensitive skin. Clinical studies on formulations containing Cupuaçu seed extract confirm their non-irritating nature on reconstructed human epidermis, further validating its excellent tolerability profile.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Theobroma Grandiflorum Fruit Extract is a valuable, well-tolerated ingredient that offers significant benefits for hydration, skin regeneration, antioxidant protection, and soothing effects across all skin types.

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