Science
Mechanism of Action
Operating primarily as a chelating agent, Tetrasodium Hydroxy Iminodisuccinate forms stable, water-soluble complexes with multivalent metal ions such as calcium, magnesium, iron, and copper. This action is crucial for preventing these ions from catalyzing the oxidation of unsaturated fatty acids within cosmetic formulations, thereby safeguarding ingredient stability, improving the bioavailability of active components, and preventing product turbidity. Additionally, it exhibits skin-soothing properties by alleviating irritations stemming from environmental stressors, which helps to reduce redness and inflammation, promoting a healthier and more uniform skin tone.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
This salt exhibits remarkable stability across a broad pH spectrum, remaining effective from weakly acidic solutions (pH > 4-7) for several hours even at 100 °C, to strongly alkaline solutions for weeks at 50 °C. A 1% aqueous solution typically presents a pH range of 10.0-11.5, ensuring its robust performance in diverse cosmetic formulations.
Conflicts
- strong oxidizing agents
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that Tetrasodium Iminodisuccinate is safe for use in cosmetics under current practices and concentrations. This assessment is supported by comprehensive data indicating its non-toxicity and non-irritating nature to the skin, eyes, and respiratory tract, with studies covering impurities, systemic toxicity, dermal irritation and sensitization, and ocular irritation.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Tetrasodium Hydroxy Iminodisuccinate is a valuable multi-functional ingredient, optimizing product stability and enhancing active ingredient performance while providing direct soothing benefits for sensitive skin.
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