Science
Mechanism of Action
The extract acts as a potent natural antioxidant, rich in vitamin E, carotenoids, chlorophyll, and tocopherols, efficiently scavenging free radicals and reactive oxygen species (ROS). It demonstrates anti-inflammatory properties by reducing pro-inflammatory factors, such as prostaglandin E2 release, and down-regulating COX-2 gene expression. Furthermore, it promotes skin regeneration and tissue repair, accelerates fibroblast maturation, and enhances cell viability in irritated epidermal tissues. It confers anti-photoaging benefits by protecting against UVB-induced damage, diminishing Matrix Metalloproteinase-1 (MMP-1) expression, and boosting pro-collagen-1 production. Sebum regulation is achieved through the repression of genes involved in fatty acid, diglyceride, triglyceride, and cholesterol synthesis. Additionally, it improves skin hydration by stimulating aquaporin 3 expression and supporting intrinsic hyaluronic acid production while inhibiting its degradation.
Research
Clinical Evidence
Medium confidence0.1%
Key findings
- 01 At a 0.1% concentration, the extract statistically downregulated 8 genes critical for lipid production (SREBF1, NR1 H3 (LXRa), APPL1, ADIPOR1, DGAT1, MGAT1, SCD, PTSG2 (COX-2)), indicating significant sebum regulation.
- 02 In human skin fibroblasts, the extract maintained 97% cell viability at 500 µg/ml and dose-dependently inhibited intracellular Reactive Oxygen Species (ROS) production in UVB-irradiated cells. It also reduced UVB-induced MMP-1 expression and protected type 1 procollagen.
- 03 A formulation containing Tetraselmis suecica extract significantly reduced sebum content, the number of fine and large pores, and improved skin microrelief and hydration after a 28-day application on oily mature skin.
- 04 A dual bioactivated marine microalgal extract, derived from Tetraselmis suecica fermented with Saccharomyces boulardii, demonstrated enhanced anti-ageing efficacy, stimulating skin's natural hyaluronic acid (HA) production, inhibiting HA degradation, regulating sebum, and providing superior antioxidant protection.
Transparency
Dusting Analysis
The Formula
Formulation
Synergies
- Enhanced anti-aging and overall efficacy when fermented with Saccharomyces boulardii.
Safety
Safety Profile
The specific combined ingredient 'TETRASELMIS SUECICA/GOLD CHLORIDE HCL LYSATE EXTRACT' lacks official review status by CIR, SCCS, or FDA. Information for general 'Tetraselmis Suecica Extract' also shows no specific status from these bodies in available data. However, it is generally rated with low irritancy and comedogenicity.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This multi-functional marine extract offers significant benefits across various skin concerns, including precise sebum control, anti-aging, robust antioxidant protection, and enhanced hydration, supported by promising clinical data.
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References
Sources