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TETRAPOTASSIUM PYROPHOSPHATE.

Valuable CAS 7320-34-5 / BUFFERING, CHELATING, ORAL CARE

Tetrapotassium Pyrophosphate is a multifunctional ingredient primarily used in skincare formulations to enhance product stability and performance. It acts as a chelating agent to neutralize detrimental metal ions, a pH regulator to maintain optimal acidity, and an emulsifier to ensure smooth, homogeneous mixtures.

buffering chelating emulsifying dispersing

Science

This ingredient functions as a chelating agent, forming complexes with metal ions that could otherwise destabilize or alter the appearance of cosmetic products. It critically regulates pH, stabilizing the product's acidity or alkalinity within a desired range. Furthermore, it aids in formulation by acting as an emulsifier, binding water and oil phases, and as a dispersing agent, preventing the re-aggregation of components.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 9.5 – 11.5
0 7 14

Stability

Tetrapotassium Pyrophosphate presents as a hygroscopic solid, maintaining stability under standard ambient storage and handling conditions. A 1% aqueous solution is notably alkaline, exhibiting a pH range of 9.5 to 11.5, which is indicative of its buffering capacity.

Conflicts

  • strong acids
  • oxidizing agents

Safety

CIR Status
Safe with restrictions
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) panel concludes that Tetrapotassium Pyrophosphate is safe for use when incorporated into non-irritating formulations. However, the CIR also notes that the comprehensive weight of evidence for skin, eye, or lung irritation remains unknown or unassessed. While the U.S. FDA classifies it as 'Generally Recognized as Safe' (GRAS) for human food consumption, with an acceptable daily intake (ADI) of 70 mg/kg of body weight per day, direct contact with high concentrations may induce skin irritation, particularly in individuals with sensitive skin, and can cause serious eye irritation.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Tetrapotassium Pyrophosphate is a valuable formulation aid, crucial for maintaining product stability, appearance, and optimal pH balance in a variety of skincare applications.


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