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Moumoujus

TETRAPEPTIDE-9.

Valuable CAS - / SKIN CONDITIONING

Tetrapeptide-9, also known as Acetyl Tetrapeptide-9, is a synthetic matrikine peptide designed to significantly enhance skin's structural integrity. It actively targets and rebuilds key components of the extracellular matrix, promoting noticeable improvements in dermal density, firmness, and elasticity for comprehensive anti-aging benefits.

Summary

Skin conditioning Anti-aging Moisturizing Evens skin tone Improves skin firmness Enhances skin elasticity Boosts collagen production Increases dermal density

Science

Mechanism of Action

This synthetic matrikine peptide modulates the metabolism of Lumican, a crucial proteoglycan vital for the precise organization of collagen fibers and the stability of the extracellular matrix. By binding to specific receptors on fibroblasts' membranes, Tetrapeptide-9 stimulates the production of both Lumican and Collagen type 1. This action leads to a denser, firmer dermal structure with enhanced organization and anchoring of collagen fibrils. Additionally, it boosts the synthesis of elastin and glycosaminoglycans, including hyaluronic acid, thereby improving skin elasticity, promoting dermal remodeling, and increasing overall moisture content.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

No data available to suggest Tetrapeptide-9 is commonly 'dusted' or used at ineffectual concentrations in formulations.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Peptides can be sensitive to specific pH levels and high temperatures, necessitating careful formulation to maintain stability and ensure efficacy.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Acetyl Tetrapeptide-9 is considered safe, effective, and very well tolerated by the epidermis, with no reported risks when used in appropriate minimal doses in formulations. The New Zealand EPA Inventory lists it as non-hazardous.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Tetrapeptide-9 is a valuable ingredient for improving skin firmness, elasticity, and density by effectively stimulating essential extracellular matrix components like Lumican and Collagen.

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