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TETRAPEPTIDE-68.

Valuable / SKIN CONDITIONING

Tetrapeptide-68 is a synthetic peptide derived from the skin structural protein Loricrin, engineered to address visible signs of aging. It works to improve skin elasticity, texture, and hydration, contributing to a more youthful complexion.

Anti-aging Wrinkle reduction Skin elasticity improvement Skin texture improvement Moisture enhancement Elastase inhibition Skin cell proliferation

Science

This peptide, designated GQVS, primarily functions as an anti-aging agent by inhibiting elastase, an enzyme crucial for the degradation of elastin—a vital protein for maintaining skin's firmness and elasticity. Furthermore, it stimulates the proliferation of skin cells, supporting cellular renewal and skin health.


Research

Medium confidence
Effective range N/A
Optimal

0.01%


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

While a specific optimal pH range for stability is not documented, Tetrapeptide-68's successful incorporation into an oil-in-water (O/W) formulation indicates good water solubility. Peptides with charged residues are generally soluble in aqueous buffers.


Safety

CIR Status
Not reviewed
Sensitization risk Low

Although peptides are generally associated with a high safety profile and low irritation potential, Tetrapeptide-68 (GQVS) has not undergone specific safety assessments by major regulatory bodies like CIR, SCCS, or FDA. The existing clinical trial reported no adverse effects.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Tetrapeptide-68 is a valuable anti-aging peptide, demonstrating significant improvements in wrinkle reduction, skin texture, and hydration in a clinical setting, making it a strong candidate for precision skincare formulations.


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