Science
Mechanism of Action
Operating as a cell-communicating signal peptide, Tetrapeptide-50 stimulates the skin's inherent repair processes. Specifically, when formulated within advanced delivery systems such as the X50 Hyalufiller complex, it significantly increases the synthesis of the Hyaluronan synthase 2 (HAS2) enzyme. This action directly leads to elevated production of endogenous hyaluronic acid and other glycosaminoglycans (GAGs). Concurrently, it promotes improved elastin synthesis, which collectively strengthens the skin's capacity to retain moisture, thereby restoring lost volume, elasticity, and overall dermal density.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Palmitoyl Tetrapeptide-50, as part of the X50 Hyalufiller complex, demonstrated efficacy in boosting hyaluronic acid and glycosaminoglycan (GAG) production by increasing Hyaluronan synthase 2 (HAS2) enzyme synthesis. This action also improved elastin production and enhanced the skin's moisture-binding ability, contributing to increased volume, elasticity, and density.
Transparency
Dusting Analysis
The provided research data does not contain information to assess dusting practices for Tetrapeptide-50.
The Formula
Formulation
Stability
Palmitoyl Tetrapeptide-50 is frequently integrated into encapsulated delivery systems, such as the 'Cosmetic Drone' technology (X50 Hyalufiller), which utilizes a polymer capsule for targeted delivery and protection. While a precise optimal pH range is not specified, peptides are generally susceptible to degradation at extreme pH values. The palmitoyl modification enhances the peptide's lipophilicity, which is crucial for improved skin penetration and overall stability within cosmetic formulations.
Safety
Safety Profile
Official assessments by the Cosmetic Ingredient Review (CIR), Scientific Committee on Consumer Safety (SCCS), or FDA specifically for Tetrapeptide-50 or Palmitoyl Tetrapeptide-50 were not identified. However, peptides as a class of ingredients are widely recognized for their high safety profile and minimal irritation potential in topical applications.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Tetrapeptide-50 is a valuable peptide for advanced skincare formulations, effectively enhancing skin's natural hyaluronic acid and elastin production, leading to improved hydration, volume, elasticity, and density across all skin types.
Related
Similar Ingredients
Finding similar ingredients…