Science
Mechanism of Action
Tetrapeptide-48 operates as a synthetic signaling peptide, instructing the skin's intrinsic mechanisms to initiate repair processes, thereby contributing to overall skin health and conditioning.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
While specific optimal pH and stability data for Tetrapeptide-48 are currently unavailable, peptides generally exhibit enhanced stability in aqueous buffer solutions within a pH range of 3-5. This range is known to minimize deamidation and oxidation, while also preserving disulfide bridge integrity. For optimal integration into formulations, peptides are typically recommended to be added after the emulsion has fully formed and cooled to an appropriate temperature.
Safety
Safety Profile
Comprehensive safety assessments for Tetrapeptide-48 by the CIR, SCCS, or FDA have not been conducted. It is important to note that the SCCS has expressed reservations regarding the safety evaluation of other platinum-containing tetrapeptides due to insufficient data, and the FDA has highlighted a lack of human safety data for certain other peptides, classifying them as 'Substance with Safety Concerns'. However, these specific concerns do not directly apply to Tetrapeptide-48 itself.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While Tetrapeptide-48 presents a promising role as a signaling peptide for skin conditioning and anti-aging, further clinical and safety evaluations are essential to fully substantiate its efficacy and establish a comprehensive risk profile.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources