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TETRAPEPTIDE-44 NICOTINATE.

Valuable / SKIN CONDITIONING

Tetrapeptide-44 Nicotinate is a multi-functional ingredient combining a skin-conditioning peptide with a niacin derivative. It is designed to enhance skin barrier integrity, promote hydration, and stimulate the skin's natural repair processes, leading to a smoother, more resilient complexion. Its anti-aging properties include supporting regeneration and visibly reducing the appearance of wrinkles.

Skin Conditioning Barrier Support Hydrating Anti-aging Regenerative Anti-inflammatory

Science

This ingredient operates through its Tetrapeptide-44 component, which actively conditions the skin and strengthens its natural barrier, leading to improved moisture retention and a refined texture. It signals the skin to activate its inherent repair mechanisms, fostering regeneration and reinforcing skin structure to visibly diminish wrinkles. While the precise action of the 'nicotinate' portion within this combined molecule is not fully elucidated, nicotinates are generally recognized for their contribution to barrier function, anti-inflammatory effects, and assistance in mitigating hyperpigmentation, suggesting a synergistic potential within Tetrapeptide-44 Nicotinate.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

CIR Status
Not reviewed
Sensitization risk Unknown

Tetrapeptide-44 is generally tolerated topically, though potential for irritation, redness, or allergic reactions exists. Patch testing is recommended prior to widespread use. Specific safety data for Tetrapeptide-44 Nicotinate, particularly regarding CIR, SCCS, or FDA review status, is not currently available. For use during pregnancy or breastfeeding, professional medical advice is advised due to insufficient research.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Low

Our Assessment

Valuable

Tetrapeptide-44 Nicotinate is a valuable ingredient for comprehensive skin health, offering significant benefits in barrier enhancement, hydration, and anti-aging due to its dual-action components.


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