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TETRAPEPTIDE-39.

Insufficient Data / SKIN CONDITIONING

TETRAPEPTIDE-39 is a sophisticated peptide engineered to bolster skin's structural integrity by stimulating the synthesis of key extracellular matrix components. It primarily targets collagen types 1 and 4, hyaluronic acid, and fibronectin, which collectively enhance skin density, elasticity, and hydration, leading to a visible reduction in wrinkles, fine lines, and skin sagging.

Anti-aging Anti-wrinkle Skin firming Skin elasticity improvement Skin density enhancement Hydration Antioxidant (general peptide property) Anti-inflammatory (general peptide property) Stretch mark reduction

Science

This tetrapeptide operates by signaling dermal fibroblasts to significantly increase their production of crucial extracellular matrix molecules, including collagen 1, collagen 4, hyaluronic acid, and fibronectin. This augmented synthesis directly contributes to enhanced skin architecture, promoting improved mechanical properties, increased density, and greater volume. Furthermore, the broader class of tetrapeptides often exhibits ancillary anti-inflammatory and antioxidant activities, with some capable of influencing neurotransmitter function to minimize expression lines.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Unknown
Optimal pH 3 – 5
0 7 14

Stability

While TETRAPEPTIDE-39's precise solubility is not specified, it is indicated that peptides within this patented group are solubilizable. To optimize general peptide stability and minimize deamidation, formulations typically benefit from a pH range between 3 and 5.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

Specific safety assessments from regulatory bodies such as CIR, SCCS, or FDA for TETRAPEPTIDE-39 are not currently available. However, tetrapeptides as a class are generally regarded as 'physiologically acceptable' for topical and transdermal cosmetic applications.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

TETRAPEPTIDE-39 demonstrates a compelling mechanism for enhancing skin structure and mitigating signs of aging, yet further specific clinical efficacy and comprehensive safety data are required for a definitive assessment.


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