Science
Mechanism of Action
TETRAPEPTIDE-38 HEXAPEPTIDE-40 DECAPEPTIDE-27 OLIGOPEPTIDE-91 DIPEPTIDE-19 SH-POLYPEPTIDE-80 exerts its effects through several key pathways. Primarily, it acts as an antioxidant, actively inhibiting oxygen-promoted reactions to prevent oxidative stress and the deterioration of other cosmetic components. Concurrently, it serves as an effective skin conditioning agent, meticulously supporting the maintenance of skin health. As a complex blend of peptides, it is hypothesized to signal the body to activate endogenous repair processes within dermal layers. This signaling is intended to drive the regeneration of mature skin, fortify its underlying structure, and contribute significantly to the visible reduction of fine lines and wrinkles in anti-aging applications.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Specific optimal pH ranges and detailed stability characteristics for this complex ingredient are not explicitly available in current research. As a general class, peptides are typically water-soluble.
Safety
Safety Profile
Comprehensive safety assessments from regulatory bodies such as the CIR (Cosmetic Ingredient Review) or SCCS (Scientific Committee on Consumer Safety) are not yet available for this specific peptide complex, resulting in its 'insufficient data' status. Paula's Choice currently lists this ingredient as 'not rated,' indicating ongoing evaluation or a lack of readily accessible comprehensive safety data. While a cosmetic product notification was found on the FDA Verification Portal for a product containing this ingredient, this signifies product registration rather than a direct safety assessment of the ingredient itself by the FDA. It is important to note a cautionary report regarding 'sh-oligopeptide-1' – a different synthetic human oligopeptide – which highlighted concerns about unsubstantiated efficacy claims and unknown long-term risks in cosmetics, underscoring the need for thorough investigation of synthetic human polypeptides.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This peptide complex presents potential as an antioxidant and skin conditioning agent with reported anti-aging benefits; however, specific clinical efficacy data and comprehensive safety assessments for this precise ingredient are currently limited, necessitating further research.
Related
Similar Ingredients
Finding similar ingredients…