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Moumoujus

TETRAPEPTIDE-17.

Valuable CAS - / SKIN CONDITIONING

Tetrapeptide-17, often identified within the TEGO Pep 4-17 blend, is a biomimetic signaling peptide engineered to activate the skin's inherent repair mechanisms. It precisely targets the stimulation of dermal collagen, hyaluronic acid, and fibronectin, visibly improving skin architecture and reducing signs of aging.

Summary

skin conditioning anti-aging collagen boosting dermal repair elasticity improvement wrinkle reduction

Science

Mechanism of Action

This peptide sequence operates by mimicking natural skin-protein breakdown products, prompting the body to initiate endogenous repair and renewal processes. By activating collagen production and stimulating dermal filling, Tetrapeptide-17 contributes to enhanced skin structure, reduced roughness, and improved elasticity.

Research

Clinical Evidence

High confidence
Effective range 0.5–5%
Optimal

N/A

Key findings

  1. 01 Clinical trials utilizing Tetrapeptide-17 at concentrations between 0.5% and 5.0% demonstrated measurable increases in skin elasticity, significant decreases in the volume of wrinkles and fine lines, and a reduction in overall skin roughness.
  2. 02 An in-vivo study conducted with 0.5% of the TEGO Pep 4-17 blend (which includes Tetrapeptide-21) showed superior improvements in skin volume, roughness, and elasticity over an 8-week period, outperforming a 10% Palmitoyl Pentapeptide-4 (Matrixyl) formulation.
  3. 03 A manufacturer's anti-wrinkle study confirmed a visible reduction of periorbital wrinkles when utilizing 4% of the TEGO Pep 4-17 blend.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

As a peptide, Tetrapeptide-17's stability can be influenced by factors such as pH, temperature, and the presence of other excipients. Degradation pathways, including oxidation or deamidation, may occur at certain pH ranges. It is typically supplied in an aqueous system containing glycerin and butylene glycol, indicating good water solubility and dispersibility.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

No specific safety assessments from CIR, SCCS, or FDA have been directly conducted for Tetrapeptide-17. While general information on peptides often suggests low irritation potential, a definitive safety profile for this specific ingredient awaits comprehensive regulatory review.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Tetrapeptide-17 is a valuable signaling peptide, clinically shown to enhance skin elasticity, reduce wrinkles, and improve overall skin texture by precisely stimulating the skin's intrinsic repair and collagen production mechanisms.

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