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Moumoujus

TETRAMETHYL-1-OXASPIRO-6-DECENE.

Questionable CAS 36431-72-8 / PERFUMING

TETRAMETHYL-1-OXASPIRO-6-DECENE is primarily recognized as a fragrance ingredient, contributing a specific aroma profile to various products. Current research indicates no identified direct cosmetic benefits or mechanism of action on skin for therapeutic purposes.

Summary

Fragrance

Science

Mechanism of Action

This compound primarily functions as a fragrance component. No explicit mechanism of action on the skin related to cosmetic benefits has been identified in the available research.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
2%%
Sensitization risk Low

The RIFM Expert Panel for Fragrance Safety has deemed 1-oxaspiro[4.5]deca-3,6-diene, 2,6,9,10-tetramethyl- (CAS 71078-31-4) safe based on their comprehensive assessment. This evaluation considered genotoxicity, repeated dose toxicity, reproductive toxicity, respiratory toxicity, photoirritation/photoallergenicity, and skin sensitization. A photo-CNIH test at 2% concentration showed no reactions in 35 subjects, suggesting no concern for photoirritation or photoallergenicity. It was also found to be non-clastogenic in an in vitro micronucleus test up to 90 μg/mL. The ingredient does not meet GHS hazard criteria and is listed as 'ACTIVE' by the EPA TSCA.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

While exhibiting a low safety risk as a fragrance component, TETRAMETHYL-1-OXASPIRO-6-DECENE lacks identified mechanisms or clinical evidence for direct skincare benefits.

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