Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

TETRAHYDROJASMONIC ACID.

Valuable / ABRASIVE, SKIN CONDITIONING

Tetrahydrojasmonic acid, also known as C-Xyloside or LR2412, is an advanced anti-aging ingredient that addresses multiple signs of skin aging by significantly improving skin hydration, enhancing elasticity, and reducing the appearance of wrinkles. It functions to fortify the skin's structural integrity and barrier function, leading to a more youthful and resilient complexion.

Summary

Skin conditioning Anti-aging Hydrating Firming Wrinkle reduction Texture improvement Skin barrier support Exfoliating

Science

Mechanism of Action

This ingredient operates via several biological pathways to promote skin rejuvenation. It notably increases epidermal hyaluronic acid by upregulating hyaluronan synthase 2 (HAS2) and HAS3, leading to enhanced skin hydration and thickness. Tetrahydrojasmonic acid reinforces the dermal-epidermal junction (DEJ) by stimulating the deposition of laminin-5, collagen IV, and fibrillin, alongside increased expression of α6-integrin and laminin-332. Furthermore, it enhances the synthesis of glycosaminoglycans, promotes skin cell proliferation, and stimulates the expression of barrier proteins like loricrin and filaggrin, contributing to a strengthened skin barrier and improved mechanical properties. It also increases collagen I and III protein expression and accelerates desquamation of the stratum corneum.

Research

Clinical Evidence

High confidence
Effective range N/A
Optimal

10%

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Tetrahydrojasmonic acid (LR2412) exhibits amphiphilic properties. While a precise optimal pH range for formulation stability is not specified, an enzyme digestion study noted activity at pH 7.4.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Clinical trials for Tetrahydrojasmonic acid (LR2412) have indicated an excellent safety profile, with no significant untoward effects reported.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Tetrahydrojasmonic acid is a valuable multi-functional ingredient demonstrating robust clinical efficacy in skin hydration, elasticity, and significant reduction of various wrinkles by strengthening the skin barrier and dermal-epidermal junction.

Related

Similar Ingredients

Finding similar ingredients…