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TETRAHYDRO-METHYL-METHYLPROPYL)-PYRAN-4-OL.

Questionable CAS 63500-71-0 / PERFUMING

This compound primarily functions as a fragrance ingredient, designed to impart a multifaceted muguet or soft floral scent. While enhancing the sensory experience, its primary utility is aromatic, offering no direct benefits to skin health or function.

Fragrance

Science

Tetrahydro-methyl-methylpropyl)-pyran-4-ol operates by introducing a soft floral or muguet olfactory note, thereby enhancing the fragrance profile of a product or directly perfuming the skin. Its action is exclusively sensorial, lacking any active dermatological mechanism.


Research

Low confidence
Effective range 0.2–1%
Optimal

0.2%


Transparency

Commonly dusted
Min. effective
0.05%
Red flag below
0.2%

Given its primary role as a fragrance and documented irritation potential, formulators may incorporate this ingredient at sub-effective concentrations (e.g., below 0.05%) to minimize adverse reactions. Any concentration at or above 0.2% is considered a red flag, as this falls within typical usage ranges where irritation risks are elevated.


The Formula

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

CIR Status
Not reviewed
Max tested
1%
Sensitization risk Moderate

Safety Data Sheets indicate this substance is classified as causing serious eye irritation (H319). It also carries the potential to cause skin irritation (H315) and allergic skin reactions (H317), with irritation likelihood increasing when combined with other problematic ingredients. Despite a 'Teen SAFE' classification by SkinSAFE, its medium irritancy profile warrants caution. The substance is not considered persistent, bioaccumulative, or toxic (PBT/vPvB).


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Questionable

As an ingredient solely providing fragrance without offering direct skin benefits, and presenting a moderate risk of irritation or allergic sensitization, its inclusion in precision skincare formulations is questionable, particularly for sensitive skin types.


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