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TETRAAMINOPYRIMIDINE SULFATE.

Avoid CAS 5392-28-9 / HAIR DYEING

Tetraaminopyrimidine Sulfate is a chemical compound primarily recognized for its application in hair coloring. It functions as a dye precursor, undergoing specific reactions to develop the final color pigment. This ingredient's utility is distinctly within hair dye formulations, lacking established functions or benefits in skincare.

Science

This compound primarily acts as a precursor in hair dyeing processes, reacting with coupler molecules to form the desired hair dye. This coloration reaction can be expedited by adding an oxidizing agent or through air exposure. There is no identified mechanism of action demonstrating direct benefits or activity on the skin for skincare applications.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 No clinical studies demonstrating efficacy for skincare purposes have been identified. Available data refers to its function as a hair color precursor, with on-head concentrations up to 3.4% (as sulfate) or 2.0% (as free base).

Transparency

Not commonly dusted

No data indicates that Tetraaminopyrimidine Sulfate is commonly 'dusted' or overhyped for skincare benefits within the cosmetic industry.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

The compound demonstrates stability under normal temperatures and pressures. Optimal storage conditions recommend room temperature, ideally in a cool, dark environment below 15°C. Comprehensive data regarding its stability specifically within various cosmetic formulations is not extensively detailed in current reviews.

Conflicts

  • strong oxidizing agents

Safety

CIR Status
Safe with restrictions
Max tested
3.4%
Sensitization risk Moderate

The Scientific Committee on Consumer Products (SCCP) deemed Tetraaminopyrimidine Sulfate safe for use in hair dye formulations, specifying a maximum on-head concentration of 2.0% (as free base) or 3.4% (as sulfate). Human tests conducted by the SCCP classified it as 'not irritating' to skin and mucous membranes and 'not-sensitizing'. However, other sources present conflicting data, including hazard statements H315 (Causes skin irritation) and H319 (Causes serious eye irritation) for the raw material. EWG also notes 'Limited evidence of skin and eye irritation' based on ECHA data, suggesting a moderate potential for irritation.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Avoid

Tetraaminopyrimidine Sulfate is exclusively a hair dye precursor with no demonstrated skincare benefits or mechanism of action. Its primary function is outside the scope of precision skincare, coupled with conflicting data regarding its irritation potential, making it an unsuitable ingredient for skin formulations.


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