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Moumoujus

TAXUS CUSPIDATA EXTRACT.

Valuable / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Taxus cuspidata Extract is a botanical active renowned for its multifaceted benefits in skincare. It exhibits potent antioxidant and anti-inflammatory properties, alongside promising anti-aging effects that include enhanced collagen synthesis and improved skin elasticity. This extract also offers depigmenting and antiallergic actions, making it a versatile ingredient for precision formulations.

Summary

Antioxidant Anti-inflammatory Skin conditioning Depigmenting Anti-aging Moisturizing Antiallergic Elastase inhibitor Collagen synthesis booster

Science

Mechanism of Action

This extract operates via several key mechanisms: it mitigates oxidative damage through its antioxidant capacity, reduces inflammation, and modulates tyrosinase activity to address hyperpigmentation. Furthermore, it supports anti-aging processes by significantly boosting collagen synthesis in fibroblasts and inhibiting elastase, thereby enhancing skin firmness and elasticity. The extract also contributes antiallergic and moisturizing effects.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In guinea pig models, Taxus cuspidata extracts demonstrated antiallergic, depigmenting, and anti-inflammatory benefits, effectively mitigating oxidative damage and regulating tyrosinase activity.
  2. 02 In vitro studies revealed a 35.43% increase in collagen synthesis by activating fibroblasts with Taxus cuspidata Sieb extract.
  3. 03 Taxus extract exhibited a 50.8% inhibition of porcine pancreatic elastase (PPE) activities, indicating a positive impact on skin elasticity.
  4. 04 Taxus seed oil demonstrated superior anti-inflammatory activity at 41.1%, surpassing the 24.2% observed with a steady glycyrrhetinate control.
  5. 05 Antioxidative activities were robust, with Taxus seed extract showing 93.7% activity via the DPPH method and 86.0% via the NBT method. These levels were notably stronger than green tea and skullcap extracts.
  6. 06 In vitro analyses of Taxus cuspidata bark extracts identified phenolic compounds (e.g., hydroxycaffeic acid, protocatechuic acid) and catechins, confirming its antioxidant bioactivities.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

This extract is soluble in both water and oil, accommodating diverse formulation needs. Reported pH values for Taxus cuspidata leaf extract are 5.3 ± 0.5, and for stem extract, 5.4 ± 0.5. Extraction can be achieved with solvents such as water, ethanol, 1,3-butylene glycol, propylene glycol, glycerin, and polyethylene glycol. Formulators should consider that chlorophyll in leaf extracts may complicate purification, and optimizing stability and bioavailability with advanced technologies is recommended.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Taxus cuspidata Extract has not undergone specific review by the Cosmetic Ingredient Review (CIR) Expert Panel or the Scientific Committee on Consumer Safety (SCCS). While the Taxus plant genus contains potent antitumor agents (taxanes) that can be toxic if ingested, cosmetic extracts are processed differently for topical application. In vitro studies have indicated low cytotoxicity, showing no adverse effects on CCK-986sk skin cell viability at concentrations up to 1,250 ppm.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Taxus cuspidata Extract is a valuable botanical ingredient offering a broad spectrum of benefits, including potent antioxidant, anti-inflammatory, anti-aging, and depigmenting effects, with a demonstrated low irritancy profile.

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