Science
Mechanism of Action
This extract's efficacy stems from its high content of polyphenols, including galloylquinic acids, flavonols, flavanols, quercetin, and myricetin glycosides. These compounds are responsible for its significant antioxidant and anti-radical properties, safeguarding skin cells from oxidative stress. Anti-inflammatory potential is inferred from the known effects of its constituent compounds. Furthermore, a methanol leaf extract has demonstrated a vasodilatory effect via the NO/cGMP pathway, involving the PI3K/Akt pathway, which could optimize microcirculation. An aqueous extract also displays targeted anti-Candida activity, while seed extracts have shown cytoprotective effects against reactive oxygen species-induced damage.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
No specific safety evaluations from major regulatory bodies such as CIR, SCCS, or FDA have been identified for this ingredient. Comprehensive oral, dermal, and inhalation toxicity data are currently unestablished. Further in vivo studies are crucial for a complete understanding of its safety profile in cosmetic applications.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While Tapirira Guianensis Leaf Extract shows promising in vitro antioxidant, potential anti-inflammatory, and microcirculation benefits, a lack of human clinical studies and comprehensive safety data necessitates further investigation before widespread recommendation.
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References
Sources