Science
Mechanism of Action
Tambourissa Trichophylla Leaf Extract operates through multiple pathways to support skin health. Its high polyphenol content contributes to significant anti-inflammatory activity, notably by inhibiting pro-inflammatory agents such as IL-17 and decreasing cathelicidin gene expression (LL37). Furthermore, it has been shown to inhibit Thymic Stromal Lymphopoietin (TSLP) secretion, a cytokine directly implicated in pruritus and the severity of atopic dermatitis, by influencing the IL-1α pathway. This extract also helps to maintain skin hydration and softness, fortifying the epidermal barrier against environmental stressors.
Research
Clinical Evidence
High confidence0.3%
Key findings
- 01 Clinical studies employing compositions with 0.3% and 0.5% of the extract demonstrated significant efficacy in reducing facial redness and blotchiness. These improvements were observed in studies involving groups of 15 volunteers over 56 days of twice-daily application.
- 02 A purified extract (Rosabora™), recommended at 0.3%, confirmed these anti-redness and anti-inflammatory benefits, unifying skin tone.
- 03 Research indicates its ability to inhibit TSLP secretion, addressing pruritus and atopic dermatitis severity, with an emphasis on its polyphenol content (over 40%, mainly troxerutin).
Transparency
Dusting Analysis
The clinically effective and recommended use concentrations for Tambourissa Trichophylla Leaf Extract are 0.3% to 0.5%, which are typically above concentrations considered for 'dusting' and align with its demonstrated efficacy.
The Formula
Formulation
Stability
This polyphenol-rich extract can be susceptible to oxidation. It is typically prepared as an aqueous solution, often using ethanol/water mixtures, followed by freeze-drying for stability.
Safety
Safety Profile
Generally recognized as safe for topical cosmetic application, with side effects being infrequent. It is specifically noted as 'Teen SAFE', 'Lip SAFE', 'Baby SAFE', and 'Irritant Free' by SkinSAFE, and free from many common allergens and irritants. As a best practice, patch testing is always recommended for individual sensitivity.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Tambourissa Trichophylla Leaf Extract is a valuable ingredient, demonstrating robust clinical efficacy in reducing redness, blotchiness, and irritation across all skin types, while simultaneously reinforcing the skin's natural barrier.
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