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Moumoujus

TAGETES MINUTA FLOWER EXTRACT.

Questionable CAS 91770-75-1 / PERFUMING

Tagetes Minuta Flower Extract, derived from the marigold plant, offers a multi-faceted approach to skin health, combining potent antioxidant and antimicrobial properties. Traditionally recognized for its soothing and healing attributes, its application requires precise formulation due to specific phototoxic considerations.

Summary

masking perfuming skin conditioning antioxidant antimicrobial antifungal

Science

Mechanism of Action

This extract functions through distinct mechanisms, including robust antioxidant activity, demonstrated by its ability to effectively scavenge reactive oxygen species (ROS) and reactive nitrogen species (RNS). It also exhibits significant antimicrobial and antifungal effects against a spectrum of pathogens. Historically, it has been associated with anti-inflammatory benefits and supporting skin repair for various minor lesions.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Inhibitory concentration (IC50) for reactive oxygen species (ROS) scavenging demonstrated in vitro at 12-17 μg/mL (Tagetes minuta essential oil).
  2. 02 Inhibitory concentration (IC50) for reactive nitrogen species (RNS) scavenging demonstrated in vitro at 200-250 μg/mL (Tagetes minuta essential oil).
  3. 03 Minimal Inhibitory Concentration (MIC) against various bacteria and fungi in vitro, including S. aureus (67 ± 8 μg/mL), B. subtilis (75 ± 7 μg/mL), C. albicans (115 ± 8 μg/mL), A. niger (135 ± 15 μg/mL), S. typhi (150 ± 8 μg/mL), and E. coli (165 ± 9 μg/mL) (Tagetes minuta essential oil).

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH 6.04 – 6.24
0 7 14

Stability

The essential oil component can polymerize and thicken upon prolonged air exposure. Optimal stability is observed within a narrow pH range around 6.04-6.24.

Conflicts

  • UV light exposure (phototoxic)
  • Sunscreens
  • Products marketed for exposure to natural/artificial UV light

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
0.01%
Sensitization risk High

The SCCS has reviewed this ingredient, noting its phototoxic nature. Consequently, its use is prohibited in sunscreen products and any products intended for use with natural or artificial UV light exposure. Maximum concentration is strictly limited to 0.01% in leave-on products and 0.1% in rinse-off products. A critical purity criterion mandates the Alpha terthienyl (terthiophen) content in the extract/oil to be ≤ 0.35%.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

While offering notable antioxidant and antimicrobial potential, the severe phototoxicity and strict regulatory limits for Tagetes Minuta Flower Extract make its safe and effective inclusion in skincare highly challenging and require extreme precision.

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