Science
Mechanism of Action
This extract functions as a powerful antioxidant by safeguarding skin from detrimental free radicals, attributed to its rich composition of flavonoids, phenyl-propanoids (such as acteoside and echinacoside), and secoiridoids (like nuzhenide and oleuropein). It delivers anti-inflammatory and soothing advantages by visibly reducing redness, discomfort, and irritation linked to conditions like eczema, sunburn, and acne. Research indicates its ability to diminish pro-inflammatory responses in neutrophils, including the production of reactive oxygen species (ROS), metalloproteinase-9 (MMP-9), interleukin 8 (IL-8), and tumor necrosis factor (TNF-α), primarily by attenuating MAP kinase pathways. Beyond these, it confers moisturizing properties, enhancing skin hydration and softness, and reinforces the skin's lipid layers and protective barrier. The extract also stimulates cell growth to promote skin regeneration, contributing to anti-aging effects by improving elasticity, firming the skin, smoothing fine lines, and lightening age spots. Its balancing attributes help normalize various skin types, including oily and blemish-prone skin, aiding in the reduction of imperfections.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Clinical studies demonstrate anti-inflammatory effects at extract concentrations ranging from 25-100 µg/mL, significantly inhibiting pro-inflammatory mediators such as ROS production, MMP-9, IL-8, and TNF-α release in a human neutrophil model. Neooleuropein was identified as a key active compound, attenuating MAP kinase pathways.
- 02 Effective antioxidant activity was observed with a flower extract at an IC50 of 36.83 µg/mL in a DPPH bleaching assay.
- 03 Ethanolic extracts at 10 mg/mL displayed strong radical scavenging activity, neutralizing 66-87% of DPPH radicals and 52-78% of ABTS cation radicals.
Transparency
Dusting Analysis
The Formula
Formulation
Synergies
- The extract's rich phytochemical profile of flavonoids and secoiridoids makes it synergistic with other antioxidant compounds and soothing agents, enhancing overall skin defense and calming effects.
Safety
Safety Profile
Syringa Vulgaris Flower Extract is generally considered a safe cosmetic ingredient, with studies indicating rare instances of allergic reactions or sensitivity. While not specifically reviewed by CIR, SCCS, or FDA, regulatory bodies such as the European Cosmetics Regulation acknowledge its safety and efficacy when used as directed. Adverse reactions are uncommon, though patch testing is recommended for individuals with highly sensitive skin.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Syringa Vulgaris Flower Extract is a valuable multi-functional ingredient offering significant antioxidant, anti-inflammatory, and balancing benefits for a wide range of skin types with a low risk profile.
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References
Sources