Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

SYNSEPALUM DULCIFICUM FRUIT EXTRACT.

Valuable CAS - / SKIN CONDITIONING

Synsepalum Dulcificum Fruit Extract, derived from the 'Miracle Berry', is a multifaceted botanical ingredient rich in beneficial phytochemicals. It offers robust antioxidant and anti-inflammatory properties, while also demonstrating potential to address hyper-pigmentation and improve hair health.

Summary

Antioxidant Anti-inflammatory Skin Brightening Skin Conditioning Hair Conditioning

Science

Mechanism of Action

This extract operates through a rich blend of phytochemicals including flavonoids, phenolics, alkaloids, saponins, glycosides, and vitamins (A, C, E). Its significant antioxidant capacity, primarily attributed to phenolic compounds and flavonoids, actively neutralizes free radicals and mitigates oxidative stress on the skin. Anti-inflammatory actions stem from compounds like flavonoids, phenolics, and beta-sitosterol. Furthermore, specific components such as (+)-epi-syringaresinol have been observed to inhibit mushroom tyrosinase activity, suggesting a pathway to reduce melanin synthesis and improve skin tone evenness.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vitro research highlights potent antioxidant activity, with a skin-pulp extract demonstrating a 52.60% DPPH radical scavenging effect (IC50 = 0.9 mg/mL).
  2. 02 Certain compounds within the fruit have shown in vitro inhibitory effects on human skin cancer cells.
  3. 03 Cosmetic applications have noted improvements in hair breakage for women with damaged hair.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Heat treatments can lead to significant losses of miraculin, the taste-modifying glycoprotein. This may imply temperature sensitivity for other beneficial components during formulation processes.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The European Food Safety Authority (EFSA) assessed dried Synsepalum dulcificum fruit as a safe novel food, with a 90-day oral toxicity study at 2,000 mg/kg body weight/day showing no adverse effects. The FDA also lists it as a food additive, and acute toxicity studies suggest low harm. However, comprehensive long-term human studies for chronic toxicity are still needed for topical applications, and pregnant or breastfeeding individuals are advised to consult a medical practitioner before use. Some individuals may experience mild allergic symptoms like itchiness, redness, or inflammation.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Synsepalum Dulcificum Fruit Extract is a valuable botanical ingredient, offering confirmed antioxidant and anti-inflammatory benefits, potential brightening effects, and good general skin compatibility.

Related

Similar Ingredients

Finding similar ingredients…