Science
Mechanism of Action
This extract primarily operates by upregulating key genes involved in skin health. It increases Aquaporin 3 (AQP-3) expression, facilitating crucial water transport within epidermal cells to improve moisture levels. It also enhances Hyaluronic Acid Synthase 3 (HAS-3) expression, promoting the skin's natural production of hyaluronic acid for superior hydration and elasticity. Furthermore, it boosts Collagen Type I Alpha 1 (COL1A1) synthesis in dermal fibroblasts, vital for maintaining skin firmness and reducing wrinkle formation. The fermented variant exhibits enhanced efficacy, partly due to increased ferulic acid content. The ingredient also acts as an antioxidant, anti-inflammatory, and antibacterial agent, inhibits melanin production for brighter skin, regulates barrier function via PPARγ activation, and prevents collagen degradation by inhibiting Matrix Metalloproteinase (MMP-1) biosynthesis.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Fermented Snowberry Leaf Extract (FSLE) at 200 μg/mL significantly increased AQP-3 gene expression by 1.57-fold in keratinocytes, demonstrating a pronounced moisturizing effect.
- 02 FSLE at 200 μg/mL elevated HAS-3 expression by 1.44-fold in keratinocytes, thereby enhancing the skin's capacity for hyaluronic acid synthesis.
- 03 In dermal fibroblasts, FSLE at 200 μg/mL led to a substantial 1.65-fold increase in COL1A1 gene expression, indicating superior anti-aging and collagen-boosting properties.
- 04 Snow fruit extract (inclusive of *Symphoricarpos albus* leaf extract) at 100 ppm inhibited matrix metalloproteinase (MMP-1) biosynthesis, contributing to wrinkle reduction and increased procollagen synthesis.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has not yet formally reviewed Symphoricarpos Albus Leaf Extract. However, studies on its efficacy, particularly using fermented extracts, imply an acceptable safety profile within experimental contexts. The fruit of Symphoricarpos albus contains saponins, which are generally poorly absorbed, suggesting low systemic toxicity; one source noted the fruit extract as 'Irritant Free,' which may indicate a low general irritancy potential for the plant.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Symphoricarpos Albus Leaf Extract, especially in its fermented form, is a valuable multi-functional ingredient for advanced skincare, offering robust hydration, significant anti-aging effects through collagen and hyaluronic acid support, and broad protective benefits.
Related
Similar Ingredients
Finding similar ingredients…