Science
Mechanism of Action
The precise mechanism of action for *Streptomyces gougerotii* Ferment Extract is not fully elucidated. However, insights from other *Streptomyces* species and general microbial fermentation extracts suggest potential multi-faceted activity. These include contributing to skin health through antioxidant defense, combating certain bacteria like *S. aureus* and MRSA, and offering anti-aging support by potentially reducing matrix metalloproteinase-1 (MMP-1) expression while stimulating procollagen type I synthesis. Broader benefits observed in other ferment extracts encompass DNA repair, anti-inflammatory actions, enhanced skin regeneration, and improved hydration.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The ferment extract demonstrates broad pH tolerance, with optimal growth of related *Streptomyces* species typically between pH 6.5-8.0, and some strains tolerating a range of pH 2.0 to 12.0. One crude extract maintained antifungal efficacy across pH 2.0 to 12.0. Specific active components may show optimal stability at pH 8.0 in aqueous solutions and solubility in organic solvents like ethyl acetate. Comprehensive stability data regarding light or oxidation for *Streptomyces gougerotii* Ferment Extract specifically is not documented.
Safety
Safety Profile
There is no dedicated safety assessment from the Cosmetic Ingredient Review (CIR) or Scientific Committee on Consumer Safety (SCCS) for *Streptomyces gougerotii* Ferment Extract. Its status with the FDA is also not specified. General assessments of 'Yeast-Derived Ingredients' by CIR are not directly applicable to this bacterial ferment extract.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While *Streptomyces gougerotii* Ferment Extract shows promising *in vitro* activities based on related species, comprehensive clinical evidence and specific safety assessments for this particular ingredient are currently lacking, warranting further research.
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References
Sources