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STREPTOCOCCUS ZOOEPIDEMICUS EXTRACT.

Valuable / HUMECTANT, SKIN CONDITIONING

Streptococcus Zooepidemicus Extract is a multi-functional ingredient derived from a bacterial fermentation process, carefully purified for cosmetic use. It delivers both hyaluronic acid for profound hydration and elasticity, and spermidine to support collagen synthesis and a healthy skin microbiome, contributing to a more youthful complexion.

Summary

skin-conditioning humectant anti-aging

Science

Mechanism of Action

This extract operates through a dual mechanism to enhance skin health. Firstly, it is a significant source of hyaluronic acid (HA), a natural polysaccharide critical for maintaining the skin's extracellular matrix. HA functions as an exceptional humectant, drawing and retaining moisture to improve skin hydration, firmness, and overall elasticity. Secondly, the extract contains spermidine, a potent metabolite scientifically recognized for its anti-aging properties. Spermidine actively stimulates collagen synthesis, essential for skin structure and resilience, and promotes lipid secretion, reinforcing the skin's protective barrier. Furthermore, spermidine may foster a balanced and beneficial skin microbiota, contributing to broader skin well-being.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Application of a Streptococcal culture supernatant on human skin demonstrably improved key phenotypes including elasticity, hydration, and desquamation. Spermidine, identified as a key metabolite within the supernatant, directly impacts skin anti-aging by activating collagen synthesis and lipid secretion, and has the potential to enhance skin conditions through modulation of beneficial skin microbes.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 6 – 7.2
0 7 14

Stability

Optimal pH conditions are crucial, particularly during the production phase, with studies indicating a range between 6.0 and 7.2 as ideal for maximizing hyaluronic acid synthesis from Streptococcus zooepidemicus. This pH range is pertinent to ingredient stability during its manufacturing.

Conflicts

  • Rigorous purification and sterilization are paramount during formulation to eliminate viable bacterial cells and their toxins, given the source organism's potential as an opportunistic pathogen. Additionally, the bacterium naturally produces hyaluronidase, an enzyme capable of degrading hyaluronic acid, necessitating control during processing to preserve HA integrity.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) has not specifically evaluated 'Streptococcus Zooepidemicus Extract'. However, regulatory bodies like the Taiwan Food and Drug Administration (TFDA) stipulate strict purity criteria for related ingredients, such as 'Streptococcus Zooepidemicus fermentation (Sodium hyaluronate)'. These require derivation from a non-hemolytic strain, complete removal of bacterial cells post-cultivation, and a final sodium hyaluronate content exceeding 87%. These guidelines underscore the critical need for extreme purity to mitigate any potential risks associated with the source organism's opportunistic pathogenic nature.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Streptococcus Zooepidemicus Extract is a valuable ingredient for enhancing skin hydration, elasticity, and anti-aging benefits through its hyaluronic acid and spermidine content, contingent upon stringent purification processes that ensure ingredient safety and efficacy.

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