Science
Mechanism of Action
The ingredient's multi-faceted mechanism stems from the synergistic properties of its fermented components. Fermented Cyclopia intermedia extract actively functions as an antioxidant by inhibiting reactive oxygen species production and demonstrates anti-wrinkle efficacy by downregulating matrix metalloproteinase activity, which reduces wrinkle length and depth, prevents epidermal thickening, and preserves collagen integrity. Concurrently, the Streptococcus thermophilus ferment contributes moisturizing properties, improves skin texture by enhancing softness and elasticity, delivers deep hydration, offers protective benefits, stimulates skin renewal, and helps to reduce inflammation. The fermentation process also yields beneficial metabolites such as L(+)-lactic acid, acetic acid, formic acid, pyruvate derivatives, and exopolysaccharides (EPS), further amplifying its antioxidant and immunomodulatory effects.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
No specific data regarding the 'dusting' of this ingredient in cosmetic formulations or common deceptive concentration ranges were identified in the available research.
The Formula
Formulation
Stability
Research on Streptococcus thermophilus fermented milk indicates a relatively stable pH range of 4.2 to 4.6 during storage. While this suggests an optimal pH environment for the fermented component, the stability of the complete complex ingredient within a final cosmetic formulation may require specific formulation-dependent assessment.
Safety
Safety Profile
Although the Cosmetic Ingredient Review (CIR) Expert Panel has not specifically evaluated this complex ingredient, related bacterial ferments such as Lactobacillus Ferment are considered safe for cosmetic use. Clinical studies on Streptococcus Thermophilus Ferment Filtrate highlight its excellent safety profile and good tolerability across most users, adhering to strict cosmetic regulations. While generally considered safe, individual sensitivities leading to mild irritation or allergic reactions are theoretically possible, thus recommending a preliminary sensitivity test. The EWG Skin Deep database lists it as 'Restricted' for EWG VERIFIED products, primarily due to a lack of adequate substantiation for their specific criteria, rather than direct safety concerns.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This complex ferment is a valuable multi-functional ingredient, offering scientifically supported antioxidant, anti-aging, and hydrating benefits for all skin types with a low risk of irritation and comedogenicity.
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References
Sources