Science
Mechanism of Action
Stevioside operates via several pathways to improve skin condition. It increases acetylcholinesterase activity, which lessens acetylcholine in the synaptic cleft, thereby reducing involuntary facial muscle contractions and diminishing horizontal wrinkles. Additionally, it exhibits anti-inflammatory, antimicrobial, and antioxidant benefits, safeguarding skin from free radical damage, minimizing redness, bolstering barrier function, and inhibiting bacterial growth. As a humectant, steviol glycosides attract and retain moisture, while natural steroid alcohols contribute astringent properties, helping to unclog and minimize pores. It can also promote collagen synthesis and protect against oxidative stress.
Research
Clinical Evidence
Medium confidence0.1-1%
Key findings
- 01 In a 30-person in-vivo test, participants experienced an average of 33% reduction in wrinkles and a 19% increase in elasticity within 28 days. (Manufacturer's test)
- 02 Significantly reduced horizontal wrinkles after 7 and 14 days of application, provided a 19% increase in hydration after 2 weeks, and improved overall skin appearance by reducing dryness, furrows, and expression lines while increasing smoothness.
- 03 A clinical trial showed improved skin hydration, brightness, smoothness, reduced fine wrinkles, and mild acne after 21 days of application.
- 04 Most effective in preserving dermal collagen against UVB-induced collagen loss in male Wistar rats.
Transparency
Dusting Analysis
The provided research does not indicate that Stevioside is commonly 'dusted' or used at ineffective concentrations simply for marketing purposes.
The Formula
Formulation
Stability
Stevioside demonstrates good stability in aqueous solutions within a pH range of 3-7 for cosmetic applications. It remains stable between pH 2-10 under thermal treatment up to 80°C, with minimal losses at the pH extremes. In solid form, it is stable up to 120°C. However, strong acidic conditions (below pH 3) can lead to significant decomposition.
Conflicts
- Very acidic formulations (below pH 3)
- Excessive amounts (above 0.5-1%) may lead to crystallization, texture issues, or bitterness.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has not specifically evaluated Stevioside. General hazard statements from PubChem suggest potential for skin irritation, allergic skin reactions, and serious eye irritation in some contexts. However, when formulated at recommended topical levels (typically 0.1-0.5%), Stevioside is considered to have a low irritation potential for cosmetic use. Concerns regarding steviol's genotoxicity were raised by the European Commission for food use, but this is not directly applicable to cosmetic topical application.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Stevioside is a valuable ingredient, offering significant anti-aging benefits, robust hydration, and soothing properties, supported by clinical findings and versatile formulation compatibility.
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