STEVIOL GLYCOSIDES/PLATYCODON GRANDIFLORUS FLOWER/ROOT EXTRACT.

The primary cutaneous benefits of this ingredient originate from the Platycodon Grandiflorus Flower/Root Extract, specifically its triterpene saponins, known as platycosides. These compounds exert anti-inflammatory effects by inhibiting the expression of inflammatory mediators such as IFN-γ, TNF-α, IL-2, and IL-1β, alongside blocking the NF-κB activation pathway. Its robust antioxidant activity is attributed to the scavenging of reactive oxygen species (ROS) and a rich content of polyphenols and flavonoids. Furthermore, the extract has been shown to promote the proliferation and migration of human dermal fibroblasts, indicating potential for wound healing and tissue regeneration. Platycodin saponins are also noted for their ability to stimulate apoptosis in skin cells. No specific dermatological mechanism for Steviol Glycosides was identified in the available research.