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Moumoujus

STEPHANIA TETRANDRA ROOT EXTRACT.

Optional CAS 223748-82-1 / SKIN CONDITIONING

Stephania Tetrandra Root Extract is a botanical ingredient recognized for its potent anti-inflammatory and antioxidant properties. It works to soothe the skin, reduce redness, and improve overall skin condition, making it a valuable addition for enhancing skin texture and appearance.

Summary

Skin Conditioning Anti-inflammatory Antioxidant Astringent Soothing

Science

Mechanism of Action

This extract contains alkaloids that primarily exert anti-inflammatory effects by modulating inflammatory pathways and inhibiting the release of allergic mediators, which can visibly reduce skin redness. Furthermore, it acts as an antioxidant, actively scavenging free radicals to protect skin cells from oxidative stress and thereby supporting healthy skin function. Its conditioning properties contribute to maintaining a soft, smooth texture, while animal studies suggest its potential to temper overactive immune responses and its astringent qualities can assist in firming the skin.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

No data suggests this ingredient is commonly used at ineffective 'dusting' percentages for its claimed benefits in topical formulations.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Formulators should be aware that Stephania Tetrandra Root Extract may present aesthetic or stability challenges that could limit its utility in certain formulations.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

Generally considered safe for topical cosmetic application, with a low irritancy and comedogenicity profile according to INCIDecoder. However, due to the potential for skin irritation, redness, or allergic reactions in sensitive individuals, a preliminary patch test is recommended prior to widespread application. For oral consumption, this ingredient carries a higher risk, with reports of kidney and liver toxicity at large doses or long-term use. Concerns also exist regarding potential misidentification with herbs containing nephrotoxic aristolochic acids, and oral use is contraindicated during pregnancy, lactation, or in cases of severe liver or kidney impairment.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Optional

Stephania Tetrandra Root Extract offers promising skin conditioning, anti-inflammatory, and antioxidant benefits, yet further clinical research on its topical efficacy at specific concentrations is needed to fully ascertain its optimal role in precision skincare.

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