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Moumoujus

STEARYLDISULFIDEHEXYL SH-DNA-3 PEG-45/SH-RNA-2.

Insufficient Data / HAIR CONDITIONING

STEARYLDISULFIDEHEXYL SH-DNA-3 PEG-45/SH-RNA-2 is a cutting-edge biotechnological ingredient, precisely engineered as a hybrid conjugate of a synthetic human RNA strand and its complementary DNA counterpart. This advanced complex is specifically designed for the targeted degradation of messenger RNA (mRNA) responsible for coding the human androgen receptor, offering a unique approach to molecular modulation.

Summary

Androgen receptor modulator Gene expression modulator

Science

Mechanism of Action

This ingredient operates via an androgen-receptor-specific small interfering RNA (siRNA) mechanism. The RNA component, comprising 19 ribonucleotides, is sequence-optimized to bind specifically to the androgen receptor mRNA. Coupled with a 19-deoxyribonucleotide complementary DNA strand, selected from the isoform-common region of human androgen receptor mRNA isoform 1, this conjugate facilitates the precise and effective degradation of its mRNA target, thereby modulating androgen receptor protein expression.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

No specific safety assessments from CIR, SCCS, or FDA are currently available for STEARYLDISULFIDEHEXYL SH-DNA-3 PEG-45/SH-RNA-2 as a whole. While polyethylene glycols (PEGs), a component of this ingredient, are generally well tolerated by the skin and are not microbiologically sensitive, specific data for this complex molecule is lacking.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

This ingredient presents a novel, highly targeted mechanism for modulating androgen receptor expression, but currently lacks comprehensive clinical efficacy and safety data specific to its application in skincare.

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