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Moumoujus

STEAROYL SARCOSINE.

Valuable CAS 142-48-3 / ANTISTATIC, CLEANSING, HAIR CONDITIONING, SURFACTANT - CLEANSING

Stearoyl Sarcosine is a sophisticated amino acid derivative that functions primarily as a surfactant, facilitating effective cleansing by emulsifying oils and impurities. Beyond its cleansing capabilities, it acts as a conditioning agent for hair and possesses the unique ability to enhance the dermal penetration of co-formulated active ingredients.

Summary

Surfactant Cleansing Agent Antistatic Agent Hair Conditioning Agent Penetration Enhancer

Science

Mechanism of Action

As an anionic surfactant, Stearoyl Sarcosine reduces the surface tension between immiscible phases, allowing water to more effectively mix with and lift oil-based dirt for thorough cleansing. Its amphiphilic nature is also posited to modulate the stratum corneum's lipid barrier, thereby enhancing the transdermal delivery and absorption of other ingredients within a formulation.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

5%

Key findings

  1. 01 A clinical study by the CIR Expert Panel demonstrated that Stearoyl Sarcosine is non-irritating and non-sensitizing in leave-on applications at concentrations up to 5%, which was the highest concentration tested.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Acyl sarcosines, including Stearoyl Sarcosine, are stronger acids than their parent fatty acids and readily form salts within the neutral to mildly acidic pH range, which contributes to their stability and functional properties.

Conflicts

  • Must not be used in cosmetic products where the formation of N-nitroso compounds is possible, due to the risk of sarcosine nitrosation into potentially carcinogenic N-nitrososarcosine.
  • Requires careful consideration when formulating with ingredients whose safety profile relies on limited dermal absorption, as Stearoyl Sarcosine can enhance the penetration of other active compounds.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
5%
Sensitization risk Low

Deemed safe for use in rinse-off products and for leave-on products at concentrations up to 5%. However, data is insufficient to establish safety in products likely to be inhaled. It is approved by the FDA for specific indirect food additive uses and is permitted in cosmetics under European Union regulations, provided general provisions are met.

Your Skin

Skin Compatibility

Yes Normal
No Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Stearoyl Sarcosine is a versatile ingredient valued for its effective cleansing, hair conditioning, and penetration-enhancing properties. It presents a low risk of irritation at tested concentrations up to 5%, provided critical formulation precautions regarding N-nitroso compound formation and enhanced dermal absorption are strictly observed.

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