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STEARAMIDOPROPYL ETHYLDIMONIUM ETHOSULFATE.

Questionable CAS 67846-16-6 / ANTISTATIC, HAIR CONDITIONING

STEARAMIDOPROPYL ETHYLDIMONIUM ETHOSULFATE is a quaternary ammonium compound primarily recognized for its antistatic and hair conditioning properties. While its direct safety data are limited, a closely related analog demonstrates potential for moisturizing effects in both rinse-off and leave-on formulations.

Antistatic Hair Conditioning

Science

This compound primarily functions by neutralizing static electricity, particularly on hair, thereby reducing flyaways and enhancing manageability. It contributes to hair conditioning, resulting in improved combability, softness, shine, and potential volume. Furthermore, it has been observed to provide a moisturizing effect in formulations designed for both rinse-off and leave-on applications.


Research

Low confidence
Effective range 0.5–4%
Optimal

N/A

Key findings

  1. 01 A clinical study on Isostearamidopropyl Ethyldimonium Ethosulfate, a closely related variant, at concentrations between 0.5% and 4%, demonstrated effective reduction in wet and dry combing forces and provided a moisturizing effect in both rinse-off and leave-on formulations.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Conflicts

  • Exhibits reduced compatibility with anionic surfactants compared to conventional quaternary compounds, though it shows improved compatibility relative to other quaternaries in its class.

Safety

CIR Status
Not reviewed
Sensitization risk Moderate

Direct CIR safety assessment for STEARAMIDOPROPYL ETHYLDIMONIUM ETHOSULFATE is currently unavailable. However, its close analog, Isostearamidopropyl Ethyldimonium Ethosulfate, is associated with potential hazards including harm if swallowed (H302), skin irritation (H315), and serious eye damage (H318) according to GHS classifications. Concerns identified for this analog by EWG include low neurotoxicity, low endocrine disruption, low-to-moderate non-reproductive organ system toxicity, low-to-moderate allergies & immunotoxicity, and low developmental and reproductive toxicity. The broader class of quaternary ammonium compounds, to which this ingredient belongs, has been implicated in reproductive effects in animal studies and altered neurodevelopment in cell models.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Medium
Comedogenicity Unknown

Our Assessment

Questionable

While offering conditioning and moisturizing benefits observed in an analog, the absence of direct safety data and identified irritancy concerns for the analog suggest a cautious approach, especially for precision skincare applications.


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