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Moumoujus

STARFISH COELOMIC FLUID EXTRACT.

Valuable / SKIN CONDITIONING

Starfish Coelomic Fluid Extract is a novel marine-derived ingredient, rich in signaling peptides, amino acids, and minerals, designed to address multiple signs of skin aging. This extract actively revitalizes aging cells and enhances skin barrier function. It delivers significant improvements in skin texture, firmness, and hydration, offering a multifaceted approach to skin rejuvenation.

Summary

Skin conditioning Anti-aging Wrinkle reduction Collagen boosting Skin firming Elasticity improvement Hydration Skin barrier repair Antioxidant Anti-inflammatory Retinol-mimetic action Anti-senescence

Science

Mechanism of Action

This potent extract functions by promoting robust collagen production and exhibiting a retinol-mimetic action without the typical associated side effects. Its mechanism involves enhancing cellular mitophagy through PINK1-dependent pathways, which leads to the suppression of senescence-associated markers such as β-galactosidase activity, matrix metalloproteinase-1 (MMP-1), and pro-inflammatory cytokines like IL-6 and IL-8 in human dermal fibroblasts. This process aids in repairing and revitalizing aging skin cells, strengthening the skin barrier, and providing protection against environmental aggressors by replenishing antioxidants.

Research

Clinical Evidence

High confidence
Effective range N/A
Optimal

1.6%

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

The extract is characterized as an odorless, colorless, and preservative-free liquid. General formulation considerations suggest potential aesthetic or stability challenges that may limit its utility in certain contexts, and the risk of irritation may be heightened when combined with specific problematic ingredients.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) has classified Starfish Coelomic Fluid Extract with 'insufficient data' for a full safety determination, suggesting potential use restrictions and data gaps. It is not listed on EWG's Skin Deep Restricted or Unacceptable Lists, nor has it been specifically evaluated by the SCCS or FDA. A clinical study at 1.6% concentration reported excellent tolerability with no signs of irritation. EWG, citing the European Chemicals Agency (ECHA), indicates a 'low' concern for irritation to skin, eyes, or lungs based on limited evidence.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Starfish Coelomic Fluid Extract is a valuable marine-derived anti-aging ingredient, clinically shown to significantly reduce wrinkles, boost elasticity, and improve hydration with a low irritation risk, despite the Cosmetic Ingredient Review (CIR) indicating insufficient data for a comprehensive safety assessment.

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