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Moumoujus

STACHYS RIEDERI ROOT EXTRACT.

Valuable / SKIN CONDITIONING

Stachys Riederi Root Extract is a robust botanical active that provides multi-faceted benefits, including potent antioxidant and cytoprotective actions against UVA-induced cellular damage. It also effectively calms skin through anti-inflammatory and anti-allergic mechanisms, making it a highly versatile ingredient for comprehensive skin health and anti-aging strategies.

Summary

Antioxidant Anti-inflammatory Soothing Anti-allergy Cytoprotective Anti-aging

Science

Mechanism of Action

Stachys Riederi Root Extract operates by directly inhibiting the production of reactive oxygen species (ROS), providing significant antioxidant defense. Its cytoprotective functions include preserving mitochondrial membrane potential, mitigating UVA-induced DNA fragmentation, and reducing caspase-3 activation. Furthermore, it modulates apoptosis by increasing Bcl-2 and decreasing Bax and cytochrome c. The extract also exerts anti-allergic and anti-inflammatory effects by suppressing mast cell activity, histamine release, and the secretion of pro-inflammatory cytokines like TNF-alpha and IL-6.

Research

Clinical Evidence

Medium confidence
Effective range ≥0.01%
Optimal

N/A

Key findings

  1. 01 A 0.01% concentration demonstrated significant inhibition of reactive oxygen species (ROS) and preserved mitochondrial membrane potential in UVA-irradiated human dermal fibroblasts (HDFs), simultaneously attenuating DNA fragmentation and caspase-3 activation, indicating strong cytoprotection.
  2. 02 Exhibited broad anti-allergic effects, including dose-dependent inhibition of systemic allergic reactions, passive cutaneous anaphylaxis, histamine release from rat peritoneal mast cells, and reduced secretion of TNF-alpha and IL-6 from stimulated human mast cells.
  3. 03 Showed efficacy in reducing wrinkles within human dermal fibroblast models.

Transparency

Dusting Analysis

Not commonly dusted

The provided research does not contain sufficient data to determine specific dusting thresholds or common dusting practices for Stachys Riederi Root Extract.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Aqueous and ethanol extracts are commonly utilized, suggesting robust stability in aqueous or hydroalcoholic formulations.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

No comprehensive safety assessments by regulatory bodies such as CIR, SCCS, or FDA are available for Stachys Riederi Root Extract.

Your Skin

Skin Compatibility

Yes Normal
No Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Stachys Riederi Root Extract is a valuable botanical active, offering comprehensive protection against environmental stressors, soothing sensitive skin, and addressing signs of aging through its multifaceted cellular benefits.

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