Science
Mechanism of Action
This extract functions by effectively inhibiting the generation of reactive oxygen species (ROS) and neutralizing free radicals, thereby mitigating oxidative stress. It safeguards human dermal fibroblasts against damage induced by UVA radiation by preserving mitochondrial membrane potential and reducing DNA fragmentation and caspase-3 activation. Furthermore, it exhibits anti-inflammatory, antibacterial, and antimicrobial properties, targeting various skin-relevant pathogens including Cutibacterium acnes, and supports wound healing processes.
Research
Clinical Evidence
Medium confidence0.01%
Transparency
Dusting Analysis
Efficacy was observed at a specific concentration (0.01%) in an in vitro study, without indications of efficacy at exceptionally low, dusting-level concentrations or widespread use patterns suggesting dusting.
The Formula
Formulation
Safety
Safety Profile
Specific safety assessments for Stachys Japonica Extract in cosmetic applications by regulatory bodies like CIR, SCCS, or FDA are currently unavailable. While some studies on other Stachys species report varied toxicity or lack thereof, the absence of dedicated cosmetic safety data necessitates caution regarding its broader application safety and potential for sensitization.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Stachys Japonica Extract is a valuable botanical ingredient, offering comprehensive protection against oxidative stress and UVA damage while possessing anti-inflammatory and antimicrobial benefits for diverse skin types.
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