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Moumoujus

SR-STAPHYLOCOCCUS PHAGE 2638A POLYPEPTIDE-1.

Insufficient Data / NOT REPORTED

SR-STAPHYLOCOCCUS PHAGE 2638A POLYPEPTIDE-1 is a sophisticated bio-peptide engineered to address both intrinsic signs of aging and the delicate balance of the skin microbiome. It functions by signaling endogenous repair processes while actively targeting problematic skin bacteria for a healthier complexion.

Summary

Skin conditioning Anti-aging Antimicrobial Microbiome balancing

Science

Mechanism of Action

This polypeptide operates through a dual mechanism. As a bioactive peptide, it precisely communicates with skin cells to activate inherent repair and regeneration pathways, leading to strengthened skin structure and a visible reduction in the appearance of wrinkles, thereby contributing to anti-aging effects. Additionally, being derived from Staphylococcal phage 2638A endolysin, it possesses specific lytic capabilities against Staphylococcus aureus, meticulously degrading its peptidoglycan cell wall to support a balanced and resilient skin microbiota.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 4 – 11
0 7 14

Stability

The polypeptide maintains general stability across a broad pH range of 4.0 to 11.0. However, it is rapidly inactivated at pH levels at or below 3.0. For optimal lytic efficiency, particularly in its antimicrobial function, a pH range of 7.0 to 8.0 is observed to be ideal for related endolysins.

Conflicts

  • Strong acids (pH ≤ 3.0)
  • High concentrations of harsh antimicrobials (e.g., chlorhexidine, hydrogen peroxide, acetic acid, povidone iodine, sodium hypochlorite), which can inactivate its bacteriophage-derived components.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Specific safety assessments for cosmetic use by major regulatory bodies such as CIR, SCCS, or FDA for SR-STAPHYLOCOCCUS PHAGE 2638A POLYPEPTIDE-1 are currently unavailable. A related ingredient, 'sr-(Methionyl Staphylococcus Simulans Polypeptide-1 Dipeptide-53 Staphylococcus Phage 2638A Polypeptide-1)', is listed on SkinSAFE as 'Irritant Free' and 'Common Preservative Free', suggesting a potentially favorable safety profile for similar phage-derived components.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

This polypeptide presents a promising dual action for anti-aging and microbiome balance; however, a comprehensive evaluation is limited by the current lack of specific clinical efficacy studies and regulatory safety assessments.

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