Science
Mechanism of Action
This recombinant polypeptide functions primarily by drawing and retaining moisture in the stratum corneum, acting as an effective humectant. It also provides skin conditioning benefits, promoting a smoother and softer feel. While specific mechanistic details for SR-SILKWORM POLYPEPTIDE-1 are not extensively documented, broader research on silkworm proteins like sericin suggests potential roles in antioxidant activity, UV protection, wound healing, and anti-inflammatory pathways. However, these broader benefits require direct substantiation for this particular recombinant form.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Specific stability data for SR-SILKWORM POLYPEPTIDE-1 are not available. However, related silkworm sericin is highly hydrophilic and typically soluble in water, especially at temperatures of 50-60°C or above. At lower temperatures, its solubility may decrease, potentially leading to conformational shifts and gel formation. These general protein stability considerations may be relevant.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has assessed numerous silk protein ingredients, such as Hydrolyzed Silk and Sericin, concluding their safety in cosmetic applications. Nevertheless, SR-SILKWORM POLYPEPTIDE-1 by its specific recombinant designation has not been explicitly covered in these reviews. While the FDA has granted GRAS status to silk fibroin from *Bombyx mori* for certain food uses, this pertains to a related but distinct ingredient and application. Specific data for this polypeptide's safety in cosmetics is limited, with some related ingredients previously deemed to have insufficient data for review.
Your Skin
Skin Compatibility
Our Assessment
Verdict
SR-SILKWORM POLYPEPTIDE-1 demonstrates potential as a hydrating and conditioning agent for all skin types, but further specific research is crucial to substantiate its efficacy and precise mechanisms beyond general silk protein properties.
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References
Sources