Science
Mechanism of Action
This complex peptide is structurally related to Fibroblast Growth Factors (FGFs) and Epidermal Growth Factors (EGFs). It is theorized to promote skin regeneration and healing by enhancing the synthesis of collagen and elastin, foundational proteins for skin firmness and elasticity. Similar peptides are known to stimulate cellular proliferation and migration, bolster the skin barrier, increase hyaluronic acid production, and aid in wound repair, suggesting a broad regenerative potential for this ingredient.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
Data not available to determine common 'dusting' practices or specific thresholds for this ingredient.
The Formula
Formulation
Stability
For optimal stability, products containing this ingredient are advised to be stored within a temperature range of 2-25°C (36-77°F), with strict avoidance of freezing and exposure to excessive heat exceeding 40°C (104°F). Peptides, particularly larger structures, often benefit from advanced delivery systems like liposomes or nanoparticles to enhance their stability, penetration into the skin, and overall efficacy.
Safety
Safety Profile
The FDA has issued a significant disclaimer, stating that products containing 'sr-Rainbow Trout Oligopeptide-1 sh-Polypeptide-13' as an active ingredient have not been determined to be safe or effective, and their labeling lacks FDA approval. The Cosmetic Ingredient Review (CIR) has not assessed this ingredient. For related peptides, long-term safety data is often limited, with some concerns regarding the scientific basis of preclinical bioactivity.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Due to explicit FDA statements indicating a lack of proven safety and efficacy, and its 'not reviewed' CIR status, the inclusion of SR-RAINBOW TROUT OLIGOPEPTIDE-1 SH-POLYPEPTIDE-13 in formulations is highly questionable.
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References
Sources