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Moumoujus

SR-RAINBOW TROUT OLIGOPEPTIDE-1 SH-POLYPEPTIDE-11.

Insufficient Data / ANTIOXIDANT, HAIR CONDITIONING, SKIN PROTECTING

The ingredient SR-RAINBOW TROUT OLIGOPEPTIDE-1 SH-POLYPEPTIDE-11 integrates a specific oligopeptide derived from rainbow trout with sh-Polypeptide-11, also known as Acidic Fibroblast Growth Factor (aFGF). This cell-signaling molecule is engineered to promote cellular regeneration, enhancing collagen and elastin production for improved skin texture, resilience, and a reduction in visible signs of aging.

Summary

Antioxidant Hair conditioning Skin protecting Cell-signaling Skin regenerating Wound healing Collagen boosting Elastin boosting Stimulates fibroblast proliferation Stimulates keratinocyte proliferation

Science

Mechanism of Action

Sh-Polypeptide-11, identified as Acidic Fibroblast Growth Factor (aFGF), functions as a critical cell-signaling protein within the dermal layers. Upon topical application, it selectively binds to specific receptors located on fibroblast cell surfaces, initiating intracellular pathways that stimulate cell proliferation and tissue regeneration. This action leads to increased dermal cell growth, significantly boosting the synthesis of collagen and elastin, thereby reinforcing the skin's extracellular matrix. Additionally, it enhances keratinocyte proliferation, supporting efficient wound healing, strengthening the skin's natural barrier functions, and contributing to the visible attenuation of fine lines and wrinkles, partly through its documented antioxidant activity.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Clinical trials have demonstrated that topical administration of rh-aFGF (sh-Polypeptide-11) effectively accelerates dermal wound healing and shortens recovery periods.
  2. 02 In-vitro studies confirm that recombinant FGF-1 (sh-Polypeptide-11) powerfully stimulates the proliferation of both fibroblasts and keratinocytes, essential cells for skin health and repair.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Comprehensive safety assessments by bodies such as CIR or SCCS specifically for SR-RAINBOW TROUT OLIGOPEPTIDE-1 SH-POLYPEPTIDE-11 are currently unavailable. It is important to note that a related product containing 'sr-Rainbow Trout Oligopeptide-1 sh-Polypeptide-13' was identified by the FDA on DailyMed as an 'unapproved drug other,' which signifies that it has not been determined as safe and effective for its stated drug purpose. This FDA status pertains to a product formulated for drug use and does not directly assess the safety of the present ingredient for cosmetic applications.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While the core component, sh-Polypeptide-11, demonstrates significant potential for skin regeneration and anti-aging benefits, comprehensive data specific to the combined SR-RAINBOW TROUT OLIGOPEPTIDE-1 formulation, particularly regarding safety and optimal use parameters, remains limited.

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