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Moumoujus

SR-ELEPHANT POLYPEPTIDE-1.

Valuable / NOT REPORTED

SR-ELEPHANT POLYPEPTIDE-1, a potent cell-signaling protein also known as Basic Fibroblast Growth Factor (bFGF), actively stimulates fibroblast proliferation to enhance skin's structural integrity. It is designed to boost collagen and elastin synthesis, promoting a more resilient and youthful complexion.

Summary

Cell-communicating ingredient Skin-conditioning Collagen synthesis stimulation Elastin synthesis stimulation Epidermal barrier reinforcement Skin renewal Promotes firmness and elasticity

Science

Mechanism of Action

This ingredient acts as a mitogenic signal, directly stimulating the growth and multiplication of fibroblasts, which are crucial for synthesizing collagen, elastin, and other extracellular matrix components vital for skin firmness and elasticity. SR-ELEPHANT POLYPEPTIDE-1 also influences keratinocyte activity by enhancing Keratinocyte Growth Factor (KGF) expression, which stimulates keratinocyte proliferation to reinforce the epidermal barrier. This comprehensive action supports skin renewal, repair, and long-term resilience.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

As a key growth factor with a potent mechanism of action, this ingredient is typically included for its active biological effects rather than for minimal 'dusting' concentrations.

The Formula

Formulation

Solubility
Water
Optimal pH 3.5 – 4
0 7 14

Stability

SR-ELEPHANT POLYPEPTIDE-1 is optimally stable and effective within a narrow acidic pH range of 3.5 to 4.0. Formulations maintaining this specific pH window are critical for maximizing its performance and stability, consistent with the requirements of other pH-dependent peptides.

Conflicts

  • Essential oils
  • Silicones
  • Fragrance/dyes
  • Solvent alcohols
  • Retinol (anecdotal user reports indicate potential allergic reactions when combined, though brands state their products containing this ingredient are generally mixable)

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) has not specifically reviewed SR-ELEPHANT POLYPEPTIDE-1. However, the CIR has assessed broader categories like 'Tissue-Derived Proteins and Peptides' and 'Plant-Derived Proteins and Peptides,' finding sufficient data to support the safety of numerous ingredients within these classes. SR-ELEPHANT POLYPEPTIDE-1 is often identified as a plant-derived signal peptide and is present in cosmetic products sold in the US, though its specific FDA status is not explicitly listed. There is a theoretical possibility of Type I immediate hypersensitivity reactions, common to protein-derived ingredients.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

SR-ELEPHANT POLYPEPTIDE-1 is a valuable cell-signaling peptide, recognized for its powerful ability to stimulate collagen and elastin production, thereby enhancing skin firmness, elasticity, and overall resilience.

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