Science
Mechanism of Action
SR-CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 SH-OLIGOPEPTIDE-1 functions by providing antioxidant protection and safeguarding the skin. Peptides within this complex are recognized for signaling the skin to activate its natural repair processes, promoting the regeneration of mature skin cells. This activation helps to strengthen the skin's underlying structure, visibly reducing wrinkles and enhancing both complexion and elasticity. The ingredient also bestows skin conditioning properties, leading to an improved epidermal texture, increased smoothness, a more uniform complexion, superior hydration, and enhanced suppleness. It contributes to the formation of a protective barrier against external environmental stressors. Specifically, the SH-Oligopeptide-1 component is a cell-communicating protein that stimulates fibroblast cell growth and proliferation, critical for synthesizing collagen and other vital extracellular matrix components.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has indicated 'insufficient data' for a comprehensive safety assessment of this specific ingredient. While generally regarded as safe for topical cosmetic use, there have been observations of potential adverse reactions, including skin irritation, redness, itching, and allergic responses; therefore, patch testing prior to widespread use is advisable. Information regarding its topical safety during pregnancy and breastfeeding is currently insufficient, and consultation with a healthcare professional is recommended. It is important to distinguish that the FDA approval for 'sr-Clostridium Botulinum Polypeptide-1' (Botox®) pertains exclusively to injectable applications for muscle relaxation, not to the topical cosmetic use of this peptide fusion. The long-term risks associated with the topical application of SH-Oligopeptide-1, a component of this ingredient, remain largely undefined.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While demonstrating theoretical promise for anti-aging, skin conditioning, and protection, definitive safety and efficacy data for the topical application of this specific ingredient are currently insufficient to fully support its widespread use.
Related
Similar Ingredients
Finding similar ingredients…