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SPIRULINA PLATENSIS EXTRACT.

Valuable CAS 223751-80-2 / SKIN PROTECTING

A precision skincare ingredient, Spirulina Platensis Extract leverages its rich antioxidant profile and essential nutrients to catalyze cellular regeneration and fortify skin's resilience. This microalgae-derived extract supports enhanced collagen synthesis and offers comprehensive protection against environmental stressors.

Antioxidant Skin protecting Humectant Anti-inflammatory Antimicrobial UV absorber

Science

Spirulina Platensis Extract functions as a robust antioxidant, employing compounds like beta-carotene and tocopherol to neutralize free radicals, thereby safeguarding skin elasticity and promoting a youthful appearance. It significantly promotes cell renewal by stimulating cell division in the basal layer, which aids in keratinization and the regeneration of the stratum corneum for smoother, more radiant skin. The extract is also observed to enhance wound healing and boost natural collagen production. It provides dermo-protective qualities, including photoprotection, and combats environmental damage. With anti-inflammatory properties, it can mitigate irritation and redness. Furthermore, it assists in detoxifying the skin by helping remove harmful substances and excess toxins, while nourishing it with vital microelements, vitamins (B12, beta-carotene), and amino acids. It improves skin hydration by enhancing water-binding capacity and reducing transdermal moisture loss, with preliminary indications of skin lightening potential through tyrosinase inhibition.


Research

Medium confidence
Effective range 0.00335–25%
Optimal

0.1%

Key findings

  1. 01 Demonstrated 198% cell viability in HS2 keratinocyte cells after 3 days, indicating robust proliferative activity.
  2. 02 When incorporated into a skin cream, it enhanced wound healing, increased cell viability, and boosted collagen 1 activity in HS2 keratinocyte cells.
  3. 03 Exhibited optimal growth stimulation, with cell activity ranging from 100% to 270% over 72 hours.
  4. 04 Anti-acne gels containing this extract showed antibacterial activity against Staphylococcus epidermidis.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 8 – 11
0 7 14

Stability

Optimal antioxidant activity is observed between pH 8.0 and 9.5, aligning with the highly alkaline conditions (pH 9-11) preferred by the raw algae for growth and optimal extraction of bioactive compounds (e.g., pH 10). While formulations for topical use are often prepared within a skin-compatible pH range of 6.5 to 7.0, the extract's intense blue color from phycocyanin can limit its cosmetic appeal, leading to the development of light-colored extracts.

Conflicts

  • Polysorbate 60 and Cremophor, when used in formulations, have been shown to induce greater toxic effects on HaCaT cells compared to sucrose ester SP 70 surfactant. General caution is advised to coordinate with other ingredients to prevent potential adverse reactions.

Safety

CIR Status
Not reviewed
Sensitization risk Low

Spirulina Platensis Extract generally exhibits a positive safety profile and has not shown genotoxic or cytotoxic effects in studies. The FDA lists Spirulina Extract as permanently exempt from certification as a color additive for food and drugs (21 CFR 73.530 and 73.1530). However, some individuals may experience mild allergic reactions or sensitivity, such as skin irritation, itching, or redness. No specific CIR or SCCS review for its cosmetic ingredient status is readily available.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

Spirulina Platensis Extract is a valuable multi-functional ingredient, offering robust cellular regeneration, potent antioxidant defense, and hydration benefits across various skin types, supporting overall skin health and resilience.


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