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Moumoujus

SPILANTHES ACMELLA EXTRACT.

Valuable CAS 90131-24-1 / SKIN CONDITIONING

Spilanthes Acmella Extract is a botanical active renowned for its potent anti-aging properties. It precisely targets expression lines by offering a mild muscle-relaxing effect while simultaneously bolstering skin's structural integrity through collagen stimulation. This multi-functional ingredient also provides antioxidant, anti-inflammatory, and hydrating benefits, making it a comprehensive solution for skin rejuvenation.

Summary

Antioxidant Anti-aging Skin-conditioning Muscle Relaxant Collagen Stimulator Anti-inflammatory Hydrating Antimicrobial

Science

Mechanism of Action

The primary active compound, spilanthol, modulates facial muscle activity to temporarily reduce contractions, thereby smoothing the appearance of fine lines and wrinkles. Beyond this 'botox-like' effect, it actively stimulates fibroblasts, promoting the synthesis of collagen for enhanced skin firmness and elasticity. Rich in antioxidants, it defends against free radical damage and mitigates hyperpigmentation, while its anti-inflammatory properties soothe the skin by inhibiting pro-inflammatory cytokines. Furthermore, it aids in moisture retention and exhibits antimicrobial action for a clearer complexion.

Research

Clinical Evidence

High confidence
Effective range 0.1–20%
Optimal

0.2%

Key findings

  1. 01 Concentrations between 0.2% and 2.0% demonstrated a reduction in wrinkles by relaxing micro-muscle tension, smoothing expression lines, and supporting collagen reorganization, with efficacy dependent on extract potency.
  2. 02 Studies indicate that concentrations ranging from 0.1% to 20% can temporarily inhibit facial muscle contractions, leading to wrinkle alleviation and improved skin smoothness and moisture, alongside antioxidant and anti-inflammatory benefits.
  3. 03 An emulgel formulation containing 2% W/W extract exhibited 100% antibacterial activity against common dermal pathogens like Staphylococcus aureus and Escherichia coli, suggesting utility in treating bacterial skin infections.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Serums incorporating Acmella oleracea extract with hyaluronic acid have shown robust stability and maintained an acceptable pH range, suitable for dermato-cosmetic applications.

Synergies

  • Hyaluronic Acid (for enhanced serum stability)

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Generally considered safe for topical cosmetic use, with a low incidence of adverse reactions. Potential side effects like irritation or redness are rare. Data regarding use during pregnancy or breastfeeding is insufficient, therefore consultation with a healthcare professional is recommended for these individuals. It has not been reviewed under the FDA's Voluntary Cosmetics Reporting Program, nor does it have GHS hazard classifications.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Spilanthes Acmella Extract is a valuable ingredient for precision skincare, effectively targeting expression lines and promoting youthful skin through its muscle-relaxing, collagen-stimulating, and antioxidant actions.

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