SORBUS COMMIXTA BRANCH EXTRACT.

Sorbus Commixta Branch Extract demonstrates robust anti-inflammatory action by modulating key cellular pathways. It suppresses nitric oxide (NO) and prostaglandin (PGE2) production via inhibition of iNOS and COX-2 gene expression, while also blocking NF-κB translocation and MAPK signaling pathways. As a potent antioxidant, it effectively scavenges various reactive oxygen species (ROS), including DPPH radicals and singlet oxygen (¹O₂), thereby safeguarding cellular membranes from oxidative damage and reducing intracellular ROS generation. Its anti-aging efficacy stems from inhibiting elastase and suppressing UVB-induced matrix metalloproteinase (MMP-1, MMP-2, MMP-3) expression, potentially stimulating collagen synthesis. Furthermore, the extract promotes skin brightening by inhibiting tyrosinase activity and supports wound healing through enhanced cell tissue formation.