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SOPHORA ANGUSTIFOLIA ROOT EXTRACT.

Valuable CAS 164288-54-4 / SKIN CONDITIONING

Sophora Angustifolia Root Extract is a potent botanical ingredient renowned for its comprehensive approach to skin brightening, effectively targeting hyperpigmentation. Beyond its melanin-regulating properties, it provides significant antioxidant protection and soothing benefits, making it suitable for a wide range of skin concerns.

Summary

Antioxidant Anti-inflammatory Skin Brightening Melanin Inhibitor Sebum Regulator Moisturizing Skin Regenerator Skin Conditioning

Science

Mechanism of Action

This extract operates via multiple synergistic pathways to enhance skin health. It acts as a powerful antioxidant, combating free radicals that accelerate premature skin aging. Its anti-inflammatory and soothing properties help to alleviate redness, irritation, and sensitivity. Crucially, it inhibits tyrosinase, the primary enzyme in melanin production, thereby reducing existing dark spots and preventing new hyperpigmentation. Further, it actively decreases melanin transfer and filopodia expression on melanocytes, showcasing a multimode action against discoloration. Additionally, it modulates sebum secretion for oily complexions and provides moisturizing and regenerative support for dry or irritated skin, functioning as a comprehensive skin conditioning agent.

Research

Clinical Evidence

Medium confidence
Effective range 0.04–1%
Optimal

N/A

Key findings

  1. 01 Clinical observations suggest that concentrations between 0.04% and 1% can effectively inhibit excess melanin production and diminish the visibility of dark spots, with a demonstrated efficacy profile similar to hydroquinone.
  2. 02 In vitro studies utilizing human melanoma cells and normal adult epidermal melanocytes showed a significant reduction in melanogenesis. Furthermore, the extract was observed to decrease melanin transfer and filopodia expression, solidifying its role as a multimode active for pigmentation concerns.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 4.5 – 7
0 7 14

Stability

The extract is water-soluble, facilitating its integration into aqueous formulations. It exhibits optimal stability within a pH range of 4.5 to 7.0, allowing for versatile product development.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) has not specifically evaluated Sophora Angustifolia Root Extract, although a closely related species is currently slated for assessment. No specific SCCS opinion or direct FDA cosmetic ingredient status has been identified. While generally considered safe for topical application, individuals with heightened skin sensitivity may experience localized reactions such as itching or redness, necessitating a prior skin sensitivity test.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Sophora Angustifolia Root Extract is a valuable, multimode active ingredient, offering significant benefits in addressing hyperpigmentation, providing antioxidant protection, and promoting skin comfort across diverse skin types.

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