Science
Mechanism of Action
This extract functions on the skin through its diverse phytochemical composition, including flavonoids, saponins, alkaloids, sterols, fatty acids, glycosides, phenolics, and tannins. It primarily exerts its effects by robustly scavenging free radicals like DPPH and ABTS, thereby mitigating oxidative stress and preventing cellular damage. Furthermore, it demonstrates anti-inflammatory actions by modulating inflammatory pathways, as evidenced in both in vitro models and animal studies. The extract also possesses antimicrobial properties, offering potential benefits against bacteria and fungi.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
No information regarding 'dusting' or insufficient usage for marketing purposes was found in the provided data.
The Formula
Formulation
Safety
Safety Profile
No specific review status by CIR, SCCS, or FDA was identified. Acute oral toxicity studies in animals indicated no toxic effects at concentrations up to 300 mg/kg, though toxicity and mortality were observed at 2000 mg/kg. In silico analyses suggest that its phytocompounds are not harmful or toxic to humans, however, specific topical human safety data for sensitization is not available.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Solanum Virginianum Extract presents as a valuable ingredient with significant in vitro and animal study support for its antioxidant and anti-inflammatory properties, offering broad compatibility across all skin types.
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References
Sources