Science
Mechanism of Action
This extract is traditionally understood to possess anti-inflammatory and diaphoretic actions, contributing to its historical application in managing skin inflammations and dermatitis. Alkaloids within the plant, such as solanine and beta-solamarine, have demonstrated *in vitro* antimicrobial activity against bacteria like *E. coli* and *S. aureus*, suggesting a potential role in addressing bacterial skin conditions. As a cosmetic ingredient, its primary function is skin conditioning.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Symptomatic relief of mild recurrent eczema when applied cutaneously as an infusion or decoction, based on over 30 years of traditional use.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
The stem extract is considered possibly safe for topical application. However, the leaves and berries of the Solanum dulcamara plant are poisonous and unsafe for oral consumption, with ingestion of the whole plant being highly toxic and potentially fatal due to compounds like solanine. While contact with the plant itself may cause skin irritation, the dermal toxicity of the isolated stem extract is not determined. The HMPC advises its use only for adults experiencing mild eczema symptoms, recommending discontinuation if symptoms persist beyond two weeks. Safety during pregnancy and lactation has not been established, and its use is not recommended during these periods.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While possessing a history of traditional use for mild eczema and anti-inflammatory properties, a lack of modern clinical data, an unreviewed safety status, and potential plant toxicity necessitate careful consideration for its inclusion in precision skincare.
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